Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | BRD4 | O60885 | 1/20 | 0.31 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11705821 | 0.90 | PAX8 (0.33) | PAX8 | |
| SCHEMBL21160122 | 0.64 | TP53 (0.37) | TSHRGAA | |
| SCHEMBL16145890 | 0.60 | ALDH1A1 (0.40) | TSHR | |
| SCHEMBL27992013 | 0.60 | PAX8 (0.39) | TSHRPAX8 | |
| SCHEMBL1781381 | 0.59 | PAX8 (0.35) | TSHRPAX8 | |
| SCHEMBL9422582 | 0.58 | — | — | |
| SCHEMBL10020855 | 0.57 | BRD4 (0.42) | TSHRBRD4GAA | |
| SCHEMBL14230616 | 0.57 | HSP90AB1 (0.37) | TSHRBRD4GAA | |
| SCHEMBL10800414 | 0.57 | ALOX15 (0.34) | TSHR | |
| SCHEMBL14441006 | 0.56 | TSHR (0.39) | TSHRBRD4GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4018797-A | Intermediates for prostaglandins | THE DOW CHEMICAL COMPANY (US) | 1977-04-19 | — | — | US | claimed |
| US-4018797-A | Intermediates for prostaglandins | THE DOW CHEMICAL COMPANY (US) | 1977-04-19 | — | — | US | disclosed |