SCHEMBL11711827

SCHEMBL11711827

CCCCCc1nc2c(c3c1CCCC3)CCCC2

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 3/20 1.00
KMT2A Q03164 3/20 1.00
ALDH1A1 P00352 5/20 0.48
L3MBTL1 Q9Y468 2/20 0.48
GAA P10253 3/20 0.46
MAPT P10636 3/20 0.46
LMNA P02545 2/20 0.46
TSHR P16473 1/20 0.42
MAPK1 P28482 1/20 0.42
KDM4E B2RXH2 5/20 0.41
HTT P42858 1/20 0.40
ATM Q13315 1/20 0.40
POLB P06746 1/20 0.38
HPGD P15428 3/20 0.38
ACHE P22303 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12507663 0.95 MEN1 (0.90) MEN1KMT2AALDH1A1L3MBTL1GAA
SCHEMBL11717674 0.91 KMT2A (0.83) MEN1KMT2AALDH1A1L3MBTL1GAA
SCHEMBL12507662 0.87 MEN1 (0.77) MEN1KMT2AALDH1A1L3MBTL1GAA
SCHEMBL12507792 0.79 MEN1 (0.65) MEN1KMT2AALDH1A1L3MBTL1GAA
SCHEMBL9405015 0.72 MEN1 (0.56) MEN1KMT2AALDH1A1L3MBTL1GAA
SCHEMBL11714630 0.70 MEN1 (0.54) MEN1KMT2AALDH1A1GAAMAPT
SCHEMBL1082422 0.69 HPGD (0.55) MEN1KMT2AALDH1A1MAPTPOLB
SCHEMBL15024799 0.69 MEN1 (0.53) MEN1KMT2AACHE
SCHEMBL14026763 0.68 PARP1 (0.56) MEN1KMT2AGAAMAPTLMNA
SCHEMBL5349652 0.67 ALDH1A1 (0.54) MEN1KMT2AALDH1A1L3MBTL1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4006236-A INSECTICIDE, MITICIDE AMERICAN CYANAMID COMPANY (US) 1977-02-01 US claimed
US-4006236-A INSECTICIDE, MITICIDE AMERICAN CYANAMID COMPANY (US) 1977-02-01 US disclosed