SCHEMBL11711878

SCHEMBL11711878

CCCCC(CC)C(=O)OCCC[Si](OCC)(OCC)OCC

nearest known ligand 0.51

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
CA2 P00918 7/20 0.51
CA1 P00915 4/20 0.51
MAPK1 P28482 1/20 0.43
ATM Q13315 2/20 0.36
GAA P10253 1/20 0.36
XBP1 P17861 1/20 0.36
NPSR1 Q6W5P4 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
USP2 O75604 1/20 0.35
ALDH1A1 P00352 1/20 0.34
TSHR P16473 2/20 0.33
CYP3A4 P08684 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
ACHE P22303 3/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL120636 0.82 CA2 (0.68) CA2CA1MAPK1ATMGAA
SCHEMBL1942106 0.82 CA2 (0.68) CA2CA1MAPK1ATMGAA
SCHEMBL304869 0.82 CA2 (0.68) CA2CA1MAPK1ATMGAA
SCHEMBL1477902 0.82 CA2 (0.68) CA2CA1MAPK1ATMGAA
SCHEMBL29528988 0.82 CA2 (0.68) CA2CA1MAPK1ATMGAA
SCHEMBL333469 0.80 CA2 (0.46) CA2CA1MAPK1ATMGAA
SCHEMBL1683137 0.80 CA2 (0.66) CA2CA1MAPK1ATMGAA
SCHEMBL4613229 0.80 CA2 (0.66) CA2CA1MAPK1TSHRACHE
SCHEMBL9736174 0.80 CA2 (0.66) CA2CA1MAPK1TSHRACHE
SCHEMBL14457777 0.80 CA2 (0.66) CA2CA1MAPK1TSHRACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1247687-C Mineral filled elastomeric compositions CROMPTON CORP (US) 2006-03-29 CN claimed
CN-1481419-A Mineral filled elastomeric compositions ��³�նٹ�˾ 2004-03-10 CN claimed
CN-101880415-B Silica-rubber mixtures having improved hardness MOMENTIVE PERFORMANCE MAT INC (US) 2013-05-22 CN disclosed
CN-1681876-B Silica-rubber mixtures with improved hardness MOMENTIVE PERFORMANCE MAT INC (US) 2012-05-30 CN disclosed
CN-101880415-A Has the silica-rubber mixtures that improves hardness MOMENTIVE PERFORMANCE MAT INC (US) 2010-11-10 CN disclosed
CN-1261494-C Silane modified biopoymerized oxidized or silicide stuffing and its production process and use DEGUSSA (DE) 2006-06-28 CN disclosed
CN-1247687-C Mineral filled elastomeric compositions CROMPTON CORP (US) 2006-03-29 CN disclosed
CN-1681876-A Silica-rubber mixtures with improved hardness GEN ELECTRIC (US) 2005-10-12 CN disclosed
CN-1481419-A Mineral filled elastomeric compositions ��³�նٹ�˾ 2004-03-10 CN disclosed
CN-1384136-A Silane modified biopoymerized oxidized or silicide stuffing and its production process and use DEGUSSA (DE) 2002-12-11 CN disclosed
US-4028384-A HYDROSILYLATION WITH A HYDROGEN SILANE, PLATINUM COMPLEX CATALYST DYNAMIT NOBEL AKTIENGESELLSCHAFT (DT) 1977-06-07 US disclosed
US-3950364-A PROCESS FOR THE PREPARATION OF ORGANIC SILICON COMPOUNDS DYNAMIT NOBEL AKTIENGESELLSCHAFT (DT) 1976-04-13 US disclosed