Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 7/20 | 0.46 |
| ▸ | CA1 | P00915 | 4/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | XBP1 | P17861 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1535793 | 0.81 | CA1 (0.38) | CA1 | |
| SCHEMBL16112256 | 0.81 | CA2 (0.59) | CA2CA1MAPK1ATMGAA | |
| SCHEMBL30325536 | 0.81 | CA2 (0.41) | CA2CA1MAPK1USP2TSHR | |
| SCHEMBL11711878 | 0.80 | CA2 (0.51) | CA2CA1MAPK1ATMGAA | |
| SCHEMBL17107098 | 0.75 | ALDH1A1 (0.31) | — | |
| 2-Ethylhexanoic Acid SCHEMBL28040207 | 0.74 | CA2 (0.48) | CA2CA1MAPK1 | |
| SCHEMBL28345852 | 0.73 | DGKA (0.41) | MAPK1TSHR | |
| SCHEMBL22028658 | 0.73 | USP2 (0.56) | CA2CA1MAPK1USP2TSHR | |
| SCHEMBL3907735 | 0.73 | CA2 (0.39) | CA2CA1MAPK1USP2TSHR | |
| 2-Ethylhexanoic Acid SCHEMBL8166134 | 0.72 | CA2 (0.57) | CA2CA1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 135 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113795499-B | Process for producing alkoxysilyl group-containing thiocarboxylate | 迈图高新材料公司 | 2024-03-19 | — | — | CN | claimed |
| US-10919920-B2 | Method for the manufacture of alkoxysilyl-containing thiocarboxylic acid esters | MOMENTIVE PERFORMANCE MATERIALS INC. (US) | 2021-02-16 | — | — | US | claimed |
| US-20200347084-A1 | METHOD FOR THE MANUFACTURE OF ALKOXYSILYL-CONTAINING THIOCARBOXYLIC ACID ESTERS | MOMENTIVE PERFORMANCE MATERIALS INC. | 2020-11-05 | — | — | US | claimed |
| EP-2978768-B1 | CATALYTIC PROCESS FOR THE PREPARATION OF THIOCARBOXYLATE SILANE | MOMENTIVE PERFORMANCE MAT INC (US) | 2017-11-29 | — | — | EP | claimed |
| EP-1341843-B2 | MINERAL-FILLED ELASTOMER COMPOSITIONS | MOMENTIVE PERFORMANCE MAT INC (US) | 2016-03-23 | — | — | EP | claimed |
| EP-1560836-B1 | PROCESS FOR MANUFACTURE OF BLOCKED MERCAPTOSILANE COUPLING AGENTS | MOMENTIVE PERFORMANCE MAT INC (US) | 2015-12-30 | — | — | EP | claimed |
| US-9206203-B2 | Catalytic process for the preparation of thiocarboxylate silane | MOMENTIVE PERFORMANCE MATERIALS INC. (US) | 2015-12-08 | — | — | US | claimed |
| US-20140296553-A1 | CATALYTIC PROCESS FOR THE PREPARATION OF THIOCARBOXYLATE SILANE | MOMENTIVE PERFORMANCE MATERIALS INC. (US) | 2014-10-02 | — | — | US | claimed |
| EP-1669401-B1 | Tire with tread containing combination of specialized elastomer and coupling agent | GOODYEAR TIRE & RUBBER (US) | 2013-07-31 | — | — | EP | claimed |
| EP-1869057-B1 | AQUEOUS CATALYTIC PROCESS FOR THE PREPARATION OF THIOCARBOXYLATE SILANE | MOMENTIVE PERFORMANCE MAT INC (US) | 2012-12-19 | — | — | EP | claimed |
| US-20030199619-A1 | Blocked mercaptosilane hydrolyzates as coupling agents for mineral-filled elastomer compositions | CROMPTON CORPORATION | 2003-10-23 | — | — | US | claimed |
| US-6635700-B2 | Mixture of a latent mercaptosilane coupling agent and an additional mercaptan activator used to cure sulfur vulcanizable rubber | CROMPTON CORPORATION | 2003-10-21 | — | — | US | claimed |
| EP-0958298-B1 | BLOCKED MERCAPTOSILANE COUPLING AGENTS FOR FILLED RUBBERS | CROMPTON CORP (US) | 2003-05-07 | — | — | EP | claimed |
| US-6528673-B2 | Reacting a mercaptosilane and a monoacid anhydride corresponding to a thioester group present in the desired product, or reacting alkali salt of a mercaptosilane with an acid anhydride or acid halide or transesterification | CROMPTON CORPORATION | 2003-03-04 | — | — | US | claimed |
| US-20020115767-A1 | Mineral-filled elastomer compositions | MOMENTIVE PERFORMANCE MATERIALS INC. | 2002-08-22 | — | — | US | claimed |
| US-20020099118-A1 | For use in tires, shoe soles | WITCO CORPORATION, A CORPORATION OF THE STATE OF DELAWARE | 2002-07-25 | — | — | US | claimed |
| US-6414061-B1 | CURABLE MIXTURE | CROMPTON CORPORATION | 2002-07-02 | — | — | US | claimed |
| US-20020055646-A1 | Reacting a mercaptosilane and a monoacid anhydride corresponding to a thioester group present in the desired product, or reacting alkali salt of a mercaptosilane with an acid anhydride or acid halide or transesterification | WITCO CORPORATION | 2002-05-09 | — | — | US | claimed |
| EP-0958298-A1 | BLOCKED MERCAPTOSILANE COUPLING AGENTS FOR FILLED RUBBERS | WITCO CORPORATION (US) | 1999-11-24 | — | — | EP | claimed |
| WO-1999009036-A1 | BLOCKED MERCAPTOSILANE COUPLING AGENTS FOR FILLED RUBBERS | OSI SPECIALTIES, INC. (US) | 1999-02-25 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140296553-A1 | CATALYTIC PROCESS FOR THE PREPARATION OF THIOCARBOXYLATE SILANE | TST, STS, CTH | CA2 151/4885CA1 132/4885MAPK1 2889/4885 |
| US-10919920-B2 | Method for the manufacture of alkoxysilyl-containing thiocarboxylic acid esters | TST, MPST, APEH | CA2 451/4885CA1 709/4885MAPK1 3658/4885 |
| US-20200347084-A1 | METHOD FOR THE MANUFACTURE OF ALKOXYSILYL-CONTAINING THIOCARBOXYLIC ACID ESTERS | TST, MPST, APEH | CA2 451/4885CA1 709/4885MAPK1 3658/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.