Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PCSK9 | Q8NBP7 | 1/20 | 0.48 |
| ▸ | LTA4H | P09960 | 2/20 | 0.46 |
| ▸ | NR1I2 | O75469 | 2/20 | 0.44 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.44 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.44 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.44 |
| ▸ | HTR2B | P41595 | 2/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.44 |
| ▸ | MLNR | O43193 | 1/20 | 0.44 |
| ▸ | ESR1 | P03372 | 1/20 | 0.44 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.44 |
| ▸ | PGR | P06401 | 1/20 | 0.44 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.44 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.44 |
| ▸ | HTR1A | P08908 | 1/20 | 0.44 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.44 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.44 |
| ▸ | DRD2 | P14416 | 1/20 | 0.44 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.44 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30545064 | 1.00 | PCSK9 (0.48) | PCSK9LTA4HNR1I2CHRM2ADRA2A | |
| SCHEMBL30545060 | 1.00 | PCSK9 (0.48) | PCSK9LTA4HNR1I2CHRM2ADRA2A | |
| SCHEMBL3289446 | 0.92 | PCSK9 (0.52) | PCSK9LTA4HNR1I2CHRM2ADRA2A | |
| SCHEMBL21658304 | 0.84 | PCSK9 (0.42) | PCSK9LTA4HNR1I2CHRM2ADRA2A | |
| SCHEMBL7796509 | 0.84 | MEN1 (0.42) | PCSK9LTA4HNR1I2CHRM2ADRA2A | |
| SCHEMBL15351802 | 0.81 | PCSK9 (0.55) | PCSK9LTA4HNR1I2CHRM2ADRA2A | |
| SCHEMBL16446602 | 0.81 | PCSK9 (0.55) | PCSK9LTA4HNR1I2CHRM2ADRA2A | |
| SCHEMBL4449195 | 0.81 | PCSK9 (0.55) | PCSK9LTA4HNR1I2CHRM2ADRA2A | |
| SCHEMBL14983388 | 0.81 | LTA4H (0.42) | PCSK9LTA4HMAPK1CYP3A4 | |
| SCHEMBL1677080 | 0.81 | PCSK9 (0.42) | PCSK9LTA4HNR1I2CHRM2ADRA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4034038-A | Boron-containing esters | THE LUBRIZOL CORPORATION (US) | 1977-07-05 | — | — | US | disclosed |