Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | ITGA4 | P13612 | 5/20 | 0.50 |
| ▸ | ITGB7 | P26010 | 5/20 | 0.50 |
| ▸ | GRK5 | P34947 | 1/20 | 0.48 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.48 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | MGLL | Q99685 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11709732 | 0.89 | ALDH1A1 (0.47) | KDM4EALDH1A1HSD17B10ITGA4ITGB7 | |
| SCHEMBL11719770 | 0.84 | MGLL (0.56) | KDM4EALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL11717725 | 0.80 | MEN1 (0.51) | KDM4EALDH1A1ITGA4ITGB7MAPT | |
| SCHEMBL11720727 | 0.80 | FAAH (0.48) | KDM4EALDH1A1HSD17B10ITGA4ITGB7 | |
| SCHEMBL11720910 | 0.80 | FAAH (0.48) | KDM4EALDH1A1HSD17B10MAPTMEN1 | |
| SCHEMBL11722069 | 0.80 | HSP90AA1 (0.48) | KDM4EALDH1A1HSD17B10MAPTMEN1 | |
| SCHEMBL9677882 | 0.80 | KDM4E (0.51) | KDM4EALDH1A1HSD17B10ITGA4ITGB7 | |
| SCHEMBL2080699 | 0.78 | GRK5 (0.68) | KDM4EALDH1A1ITGA4ITGB7GRK5 | |
| SCHEMBL4925270 | 0.76 | MAPT (0.58) | KDM4EALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL11717871 | 0.73 | HPN (0.59) | KDM4EALDH1A1MAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4053620-A | COMBATING FUNGI WITH 1-ARYL-5-ALKYLIDENE-2,4-DIOXO-IMIDAZOLIDINES | BAYER AKTIENGESELLSCHAFT (DT) | 1977-10-11 | — | — | US | claimed |
| CN-105523958-B | A kind of method for preparing Diarylthiohydantoin derivative key intermediate | 北京海步医药科技股份有限公司 | 2017-11-03 | — | — | CN | disclosed |
| CN-105523958-A | Method for preparing key intermediate of diarylthiohydantoin derivative | BEIJING HOPE PHARMACEUTICAL CO LTD | 2016-04-27 | — | — | CN | disclosed |
| US-4053620-A | COMBATING FUNGI WITH 1-ARYL-5-ALKYLIDENE-2,4-DIOXO-IMIDAZOLIDINES | BAYER AKTIENGESELLSCHAFT (DT) | 1977-10-11 | — | — | US | disclosed |
| US-4036850-A | FUNGICIDES, HERBICIDES, BACTERICIDES | BAYER AKTIENGESELLSCHAFT (DT) | 1977-07-19 | — | — | US | disclosed |