Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17706711 | 1.00 | HSD17B10 (0.43) | HSD17B10TDP1POLBMAPK1SMN1; SMN2 | |
| SCHEMBL8562008 | 1.00 | HSD17B10 (0.43) | HSD17B10TDP1POLBMAPK1SMN1; SMN2 | |
| SCHEMBL31532972 | 0.91 | L3MBTL1 (0.41) | HSD17B10TDP1POLBMAPK1SMN1; SMN2 | |
| SCHEMBL16415859 | 0.89 | MAPT (0.50) | HSD17B10TDP1POLBMAPK1L3MBTL1 | |
| SCHEMBL28295367 | 0.89 | DPP7 (0.46) | HSD17B10TDP1POLBMAPK1SMN1; SMN2 | |
| SCHEMBL8625882 | 0.89 | DPP7 (0.46) | HSD17B10TDP1POLBMAPK1SMN1; SMN2 | |
| Aspartic Acid SCHEMBL1959842 | 0.88 | DPP7 (0.46) | HSD17B10 | |
| Aspartic Acid SCHEMBL150400 | 0.88 | DPP7 (0.46) | HSD17B10 | |
| SCHEMBL4372205 | 0.88 | HSD17B10 (0.37) | HSD17B10TDP1POLBMAPK1L3MBTL1 | |
| SCHEMBL15780321 | 0.88 | SLC6A9 (0.45) | HSD17B10TDP1POLBMAPK1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4052384-A | MAGNESIUM OR CALCIUM OXIDE TRANSESTERIFICATION CATALYST | BASF AKTIENGESELLSCHAFT (DT) | 1977-10-04 | — | — | US | claimed |
| US-4013480-A | RING-OPENED AZIRIDINYL HOMOPOLYMERS | THE DOW CHEMICAL COMPANY (US) | 1977-03-22 | — | — | US | disclosed |