Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Aspartic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.46 |
| ▸ | GRIK1 | P39086 | 8/20 | 0.39 |
| ▸ | GRIK2 | Q13002 | 3/20 | 0.39 |
| ▸ | GRM1 | Q13255 | 2/20 | 0.39 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.39 |
| ▸ | GRIA4 | P48058 | 3/20 | 0.38 |
| ▸ | GRIK3 | Q13003 | 3/20 | 0.38 |
| ▸ | GRIK5 | Q16478 | 3/20 | 0.38 |
| ▸ | GRIA1 | P42261 | 2/20 | 0.38 |
| ▸ | GRIA2 | P42262 | 2/20 | 0.38 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.38 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.38 |
| ▸ | GRM8 | O00222 | 1/20 | 0.38 |
| ▸ | GRM6 | O15303 | 1/20 | 0.38 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.38 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.38 |
| ▸ | GSR | P00390 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | GRM5 | P41594 | 1/20 | 0.38 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Aspartic Acid SCHEMBL1959842 | 1.00 | DPP7 (0.46) | DPP7GRIK1GRIK2GRM1GRM2 | |
| SCHEMBL11713448 | 0.88 | HSD17B10 (0.43) | HSD17B10 | |
| SCHEMBL17706711 | 0.88 | HSD17B10 (0.43) | HSD17B10 | |
| SCHEMBL8562008 | 0.88 | HSD17B10 (0.43) | HSD17B10 | |
| Glutamic Acid SCHEMBL8560921 | 0.86 | GRM8 (0.60) | DPP7GRIK1GRIK2GRM1GRM2 | |
| SCHEMBL8769759 | 0.83 | DPP7 (0.36) | DPP7GRIK1GRIK2GRM1GRM2 | |
| SCHEMBL31532972 | 0.79 | L3MBTL1 (0.41) | DPP7HSD17B10 | |
| Aspartic Acid SCHEMBL4321763 | 0.79 | GRIK1 (0.52) | GRIK1GRIK2GRM1GRM2GRIA4 | |
| SCHEMBL16415859 | 0.78 | MAPT (0.50) | CYP1A2HSD17B10 | |
| Aspartic Acid SCHEMBL3231 | 0.78 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120055873-A1 | GREEN SYNTHESIS OF NANOMETALS USING PLANT EXTRACTS AND USE THEREOF | The U.S.A as represented by the Administrator of the U.S. Environmental Protection Agency (US) | 2012-03-08 | — | — | US | disclosed |
| US-8057682-B2 | Green synthesis of nanometals using plant extracts and use thereof | VERUTEK TECHNOLOGIES, INC. (US) | 2011-11-15 | — | — | US | disclosed |
| EP-2315639-A2 | GREEN SYNTHESIS OF NANOMETALS USING PLANT EXTRACTS AND USE THEREOF | Verutek Technologies, Inc. (US) | 2011-05-04 | — | — | EP | disclosed |
| US-20100200501-A1 | GREEN SYNTHESIS OF NANOMETALS USING PLANT EXTRACTS AND USE THEREOF | VERUTEK TECHNOLOGIES ,INC. (US) | 2010-08-12 | — | — | US | disclosed |
| WO-2009140694-A2 | GREEN SYNTHESIS OF NANOMETALS USING PLANT EXTRACTS AND USE THEREOF | VERUTEK TECHNOLOGIES, INC. (US) | 2009-11-19 | — | — | WO | disclosed |