Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.48 |
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 3/20 | 0.45 |
| ▸ | GAA | P10253 | 3/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.42 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26608016 | 0.87 | ALDH1A1 (0.51) | ALDH1A1MAPTL3MBTL1LMNAPOLB | |
| SCHEMBL13534290 | 0.77 | MAPT (0.55) | ALDH1A1MAPTL3MBTL1LMNAPOLB | |
| SCHEMBL8045280 | 0.76 | HPGD (0.41) | ALDH1A1LMNAPOLBCYP2C19 | |
| SCHEMBL26084791 | 0.74 | ALDH1A1 (0.44) | ALDH1A1MAPTL3MBTL1LMNAPOLB | |
| SCHEMBL10510362 | 0.72 | SMN1; SMN2 (0.50) | ALDH1A1MAPTLMNACYP2C19KMT2A | |
| SCHEMBL31091468 | 0.70 | KMT2A (0.58) | ALDH1A1MAPTL3MBTL1LMNAPOLB | |
| SCHEMBL7547086 | 0.69 | MAPT (0.53) | ALDH1A1MAPTL3MBTL1LMNAPOLB | |
| SCHEMBL16703811 | 0.69 | KMT2A (0.53) | ALDH1A1MAPTL3MBTL1LMNAPOLB | |
| SCHEMBL31091467 | 0.68 | KMT2A (0.47) | ALDH1A1MAPTL3MBTL1LMNAPOLB | |
| SCHEMBL28525283 | 0.68 | KMT2A (0.56) | ALDH1A1MAPTL3MBTL1LMNAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4008221-A | BACTERICIDE, ANTIBIOTIC | RICHARDSON-MERRELL INC. (US) | 1977-02-15 | — | — | US | disclosed |
| US-3956288-A | 7-[(2,4-Dioxo-1-pyrimidinyl)acylamino]cephalosporin derivatives | RICHARDSON-MERRELL INC. (US) | 1976-05-11 | — | — | US | disclosed |