Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | TYMP | P19971 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | ALB | P02768 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | MET | P08581 | 1/20 | 0.38 |
| ▸ | TK1 | P04183 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28985694 | 0.85 | TYMP (0.40) | HPGDTYMPALDH1A1LMNAALB | |
| SCHEMBL31389027 | 0.84 | TK1 (0.37) | HPGDTYMPALDH1A1LMNAALB | |
| SCHEMBL10510362 | 0.81 | SMN1; SMN2 (0.50) | ALDH1A1LMNAMETCYP2C19 | |
| SCHEMBL3930328 | 0.81 | HPGD (0.43) | HPGDTYMPALDH1A1LMNAALB | |
| SCHEMBL9155069 | 0.80 | TYMP (0.43) | HPGDTYMPALDH1A1LMNAALB | |
| SCHEMBL784395 | 0.80 | MAPK1 (0.43) | HPGDTYMPALDH1A1LMNAALB | |
| SCHEMBL7195434 | 0.79 | TK1 (0.38) | HPGDTYMPALDH1A1LMNAALB | |
| SCHEMBL22759941 | 0.77 | MAPK1 (0.41) | HPGDTYMPALDH1A1LMNAALB | |
| SCHEMBL4194708 | 0.77 | MAPK1 (0.41) | HPGDTYMPALDH1A1LMNAALB | |
| SCHEMBL11713686 | 0.76 | ALDH1A1 (0.48) | ALDH1A1LMNAPOLBCYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6084082-A | SOLID PHASE SYNTHESIS BY ATTACHING BETA-LACTAM HAVING NUCLEOBASE TO SOLID SUPPORT, DEPROTECTING HYDROXY GROUP, REACTING FREE HYDROXYL GROUP WITH BETA-LACTAMTIDE HAVING ACTIVATED PHOSPHITE GROUP, AND OXIDIZING | ISIS PHARMACEUTICALS, INC. (US) | 2000-07-04 | — | — | US | disclosed |
| WO-2000002864-A1 | PRECUSORS FOR PNA-MONOMERS | MARTENS JUERGEN (DE) | 2000-01-20 | — | — | WO | disclosed |
| US-5866691-A | Lactam nucleic acids | ISIS PHARMACEUTICALS, INC. (US) | 1999-02-02 | — | — | US | disclosed |
| US-5554746-A | Lactam nucleic acids | ISIS PHARMACEUTICALS, INC. (US) | 1996-09-10 | — | — | US | disclosed |
| US-4008221-A | BACTERICIDE, ANTIBIOTIC | RICHARDSON-MERRELL INC. (US) | 1977-02-15 | — | — | US | disclosed |
| US-3956288-A | 7-[(2,4-Dioxo-1-pyrimidinyl)acylamino]cephalosporin derivatives | RICHARDSON-MERRELL INC. (US) | 1976-05-11 | — | — | US | disclosed |