Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDC25B | P30305 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | EDNRB | P24530 | 6/20 | 0.39 |
| ▸ | EDNRA | P25101 | 6/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15113560 | 0.81 | KDM4E (0.49) | CDC25BKDM4EALDH1A1HPGDNPSR1 | |
| SCHEMBL11829450 | 0.77 | ALDH1A1 (0.40) | CDC25BKDM4EALDH1A1HPGDNPSR1 | |
| SCHEMBL756469 | 0.75 | ALOX15 (0.46) | CDC25BKDM4EALDH1A1HPGDNPSR1 | |
| SCHEMBL11713317 | 0.71 | AKR1C3 (0.41) | KDM4EALDH1A1KMT2AMEN1EDNRB | |
| SCHEMBL3838553 | 0.71 | KDM4E (0.52) | CDC25BKDM4EALDH1A1HPGDNPSR1 | |
| SCHEMBL11711474 | 0.69 | AKR1C3 (0.39) | KDM4EALDH1A1EDNRBEDNRAMAPT | |
| SCHEMBL4266314 | 0.69 | KDM4E (0.53) | KDM4EALDH1A1HPGDNPSR1CYP1A2 | |
| SCHEMBL637337 | 0.69 | KDM4E (0.53) | KDM4EALDH1A1HPGDNPSR1KMT2A | |
| SCHEMBL24373348 | 0.68 | KDM4E (0.49) | KDM4EALDH1A1HPGDNPSR1KMT2A | |
| SCHEMBL4102841 | 0.68 | KDM4E (0.49) | KDM4EALDH1A1HPGDNPSR1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4053476-A | 7-AZA-6-ALKOXY-1-TETRALONES | G. D. SEARLE & CO. (US) | 1977-10-11 | — | — | US | disclosed |
| US-3991061-A | Azanaphthaleneacetic acid derivatives | G. D. SEARLE & CO. (US) | 1976-11-09 | — | — | US | disclosed |