Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.53 |
| ▸ | BTK | Q06187 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.42 |
| ▸ | BRD7 | Q9NPI1 | 1/20 | 0.42 |
| ▸ | NQO1 | P15559 | 1/20 | 0.41 |
| ▸ | NR1I3 | Q14994 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | VDR | P11473 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.41 |
| ▸ | AHR | P35869 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11618442 | 0.98 | KDM4E (0.52) | KDM4EBTKALDH1A1CYP1A2CYP2C19 | |
| Sodium Chloride SCHEMBL10660756 | 0.93 | KDM4E (0.47) | KDM4EBTKALDH1A1CYP1A2CYP2C19 | |
| SCHEMBL13763671 | 0.84 | BTK (0.44) | KDM4EBTKALDH1A1CYP1A2CYP2C19 | |
| SCHEMBL13409319 | 0.84 | BTK (0.50) | KDM4EBTKALDH1A1CYP1A2CYP2C19 | |
| SCHEMBL26132370 | 0.82 | BTK (0.48) | KDM4EBTKALDH1A1CYP1A2CYP2C19 | |
| SCHEMBL13443806 | 0.80 | BTK (0.49) | KDM4EBTKALDH1A1CYP1A2CYP2C19 | |
| SCHEMBL637337 | 0.80 | KDM4E (0.53) | KDM4EALDH1A1CYP1A2CYP2C19NQO1 | |
| SCHEMBL161865 | 0.78 | BTK (0.48) | KDM4EBTKALDH1A1CYP1A2CYP2C19 | |
| SCHEMBL18687685 | 0.78 | BTK (0.48) | KDM4EBTKALDH1A1CYP1A2CYP2C19 | |
| SCHEMBL5656369 | 0.78 | BTK (0.48) | KDM4EBTKALDH1A1CYP1A2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 87 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180021334-A1 | USE OF ERGOT ALKALOIDS AS AN ANTHELMINTIC AGENT | REGENTS OF THE UNIVERSITY OF MINNESOTA | 2018-01-25 | — | — | US | claimed |
| CN-101973991-B | Preparation method of fibrauretine | TAICANG PUYUAN PHARMACEUTICAL RAW MATERIAL CO LTD | 2012-07-25 | — | — | CN | claimed |
| CN-101973991-A | Preparation method of fibrauretine | TAICANG PUYUAN PHARMACEUTICAL RAW MATERIAL CO LTD | 2011-02-16 | — | — | CN | claimed |
| CN-101285061-A | Fungal cell wall synthetic genes | EISAI R&D MAN CO LTD (JP) | 2008-10-15 | — | — | CN | claimed |
| CN-1249227-C | Fungal cell wall synthetic genes | EISAI CO LTD (JP) | 2006-04-05 | — | — | CN | claimed |
| CN-1449443-A | Fungal cell wall synthetic genes | EISAI CO LTD (JP) | 2003-10-15 | — | — | CN | claimed |
| EP-0158312-B1 | 1-CYCLOHEXYL-3,4-DIHYDROISOQUINOLINE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND MEDICAMENT CONTAINING THEM | RICHTER GEDEON VEGYESZETI GYAR R.T. (HU) | 1990-09-12 | — | — | EP | claimed |
| CN-1008738-B | The preparation method of cephalosporins derivatives | BANYU PHARMA CO LTD (JP) | 1990-07-11 | — | — | CN | claimed |
| CN-85109545-A | Process for preparing cephalosporin derivatives | — | 1986-07-23 | — | — | CN | claimed |
| US-10426772-B2 | Use of ergot alkaloids as an anthelmintic agent | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 2019-10-01 | — | — | US | disclosed |
| US-10426772-B2 | Use of ergot alkaloids as an anthelmintic agent | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 2019-10-01 | — | — | US | disclosed |
| US-20180021334-A1 | USE OF ERGOT ALKALOIDS AS AN ANTHELMINTIC AGENT | REGENTS OF THE UNIVERSITY OF MINNESOTA | 2018-01-25 | — | — | US | disclosed |
| US-20180021334-A1 | USE OF ERGOT ALKALOIDS AS AN ANTHELMINTIC AGENT | REGENTS OF THE UNIVERSITY OF MINNESOTA | 2018-01-25 | — | — | US | disclosed |
| WO-2017049409-A1 | COMPOSITIONS FOR PROMOTING READTHROUGH OF PREMATURE TERMINATION CODONS, AND METHODS OF USING THE SAME | THE CENTRE FOR DRUG RESEARCH AND DEVELOPMENT (CA) | 2017-03-30 | — | — | WO | disclosed |
| CN-1081181-A | Acridine derivatives | GLAXO LAB SA (FR) | 1994-01-26 | — | — | CN | disclosed |
| CN-1061411-A | Be used to strengthen the active quinazoline derivant of antineoplastic agent | PFIZER (US) | 1992-05-27 | — | — | CN | disclosed |
| EP-0158312-B1 | 1-CYCLOHEXYL-3,4-DIHYDROISOQUINOLINE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND MEDICAMENT CONTAINING THEM | RICHTER GEDEON VEGYESZETI GYAR R.T. (HU) | 1990-09-12 | — | — | EP | disclosed |
| CN-1008738-B | The preparation method of cephalosporins derivatives | BANYU PHARMA CO LTD (JP) | 1990-07-11 | — | — | CN | disclosed |
| CN-85109545-A | Process for preparing cephalosporin derivatives | — | 1986-07-23 | — | — | CN | disclosed |
| US-3994891-A | VASODILATORS | ARMOUR PHARMACEUTICAL COMPANY (US) | 1976-11-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180021334-A1 | USE OF ERGOT ALKALOIDS AS AN ANTHELMINTIC AGENT | HNMT, GNMT, AADAT | KDM4E 1387/4885BTK 4778/4885ALDH1A1 2404/4885 |
| US-10426772-B2 | Use of ergot alkaloids as an anthelmintic agent | HNMT, AADAT, GNMT | KDM4E 928/4885BTK 4757/4885ALDH1A1 2314/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.