Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.55 |
| ▸ | LMNA | P02545 | 3/20 | 0.55 |
| ▸ | MAPT | P10636 | 4/20 | 0.52 |
| ▸ | POLB | P06746 | 2/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.52 |
| ▸ | FEN1 | P39748 | 1/20 | 0.52 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 5/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 5/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 4/20 | 0.47 |
| ▸ | HDAC11 | Q96DB2 | 4/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.47 |
| ▸ | NCOR2 | Q9Y618 | 4/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11719981 | 0.96 | ALDH1A1 (0.56) | ALDH1A1KDM4ELMNAMAPTPOLB | |
| SCHEMBL11713364 | 0.93 | ALDH1A1 (0.60) | ALDH1A1KDM4ELMNAMAPTPOLB | |
| SCHEMBL11715781 | 0.88 | MAPT (0.55) | ALDH1A1KDM4ELMNAMAPTPOLB | |
| SCHEMBL11710399 | 0.88 | ALDH1A1 (0.60) | ALDH1A1KDM4ELMNAMAPTPOLB | |
| SCHEMBL11713438 | 0.87 | KMT2A (0.50) | ALDH1A1KDM4ELMNAMAPTPOLB | |
| SCHEMBL11718999 | 0.81 | L3MBTL1 (0.64) | ALDH1A1KDM4ELMNAMAPTPOLB | |
| SCHEMBL11714377 | 0.80 | ALDH1A1 (0.56) | ALDH1A1KDM4ELMNAMAPTPOLB | |
| SCHEMBL11711675 | 0.79 | KMT2A (0.54) | ALDH1A1KDM4ELMNAMAPTPOLB | |
| SCHEMBL11711376 | 0.79 | ALDH1A1 (0.56) | ALDH1A1KDM4ELMNAMAPTPOLB | |
| SCHEMBL11717796 | 0.78 | CYP1B1 (0.60) | ALDH1A1KDM4ELMNAMAPTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4055565-A | Optical brightening agents of naphthalimide derivatives | SUMITOMO CHEMICAL COMPANY, LIMITED (JA) | 1977-10-25 | — | — | US | disclosed |