Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 11/20 | 0.68 |
| ▸ | RAB9A | P51151 | 6/20 | 0.68 |
| ▸ | TP53 | P04637 | 4/20 | 0.68 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.68 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.68 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.68 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.68 |
| ▸ | RELA | Q04206 | 2/20 | 0.68 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.68 |
| ▸ | NPC1 | O15118 | 5/20 | 0.65 |
| ▸ | MEN1 | O00255 | 6/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.58 |
| ▸ | HPGD | P15428 | 5/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.58 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.54 |
| ▸ | GAA | P10253 | 2/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11714556 | 0.86 | NR1H4 (0.64) | MAPTRAB9ATP53SMN1; SMN2NFKB1 | |
| SCHEMBL28653242 | 0.82 | SMN1; SMN2 (1.00) | MAPTRAB9ATP53SMN1; SMN2NFKB1 | |
| SCHEMBL29859163 | 0.79 | SMN1; SMN2 (0.81) | MAPTRAB9ATP53SMN1; SMN2NFKB1 | |
| SCHEMBL3430034 | 0.79 | SMN1; SMN2 (0.81) | MAPTRAB9ATP53SMN1; SMN2NFKB1 | |
| SCHEMBL11712483 | 0.79 | NR1H4 (0.61) | MAPTRAB9ATP53SMN1; SMN2NFKB1 | |
| SCHEMBL11711972 | 0.79 | NPC1 (0.61) | MAPTRAB9ATP53SMN1; SMN2NFKB1 | |
| SCHEMBL11711449 | 0.79 | TPH1 (0.56) | MAPTRAB9ATP53SMN1; SMN2NFKB1 | |
| SCHEMBL11709774 | 0.78 | CA2 (0.60) | MAPTRAB9ATP53SMN1; SMN2MAPK1 | |
| SCHEMBL11711722 | 0.77 | SMN1; SMN2 (0.68) | MAPTRAB9ATP53SMN1; SMN2NFKB1 | |
| SCHEMBL27379300 | 0.77 | MAPT (0.73) | MAPTRAB9ATP53SMN1; SMN2NFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4003909-A | [(1,2,4-Oxadiazol-3-yl)phenyl]carbamic or thiocarbamic acid esters | E. R. SQUIBB & SONS, INC. (US) | 1977-01-18 | — | — | US | disclosed |