Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 9/20 | 0.61 |
| ▸ | MEN1 | O00255 | 8/20 | 0.61 |
| ▸ | USP2 | O75604 | 4/20 | 0.61 |
| ▸ | KEAP1 | Q14145 | 2/20 | 0.61 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.61 |
| ▸ | NPC1 | O15118 | 1/20 | 0.61 |
| ▸ | RAB9A | P51151 | 1/20 | 0.61 |
| ▸ | ATM | Q13315 | 1/20 | 0.61 |
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | RGS12 | O14924 | 2/20 | 0.48 |
| ▸ | RECQL | P46063 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | BLM | P54132 | 1/20 | 0.46 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11710441 | 0.89 | MAPT (0.56) | KMT2AMEN1USP2KEAP1NFE2L2 | |
| SCHEMBL11712893 | 0.88 | KMT2A (0.56) | KMT2AMEN1USP2KEAP1NFE2L2 | |
| SCHEMBL11715762 | 0.88 | KMT2A (0.51) | KMT2AMEN1USP2KEAP1NFE2L2 | |
| SCHEMBL25214387 | 0.81 | LMNA (0.67) | KMT2AMEN1RAB9AMAPTLMNA | |
| SCHEMBL11251050 | 0.81 | MEN1 (0.65) | KMT2AMEN1USP2KEAP1NFE2L2 | |
| SCHEMBL11720182 | 0.80 | ALDH1A1 (0.57) | KMT2AMEN1MAPTLMNARECQL | |
| SCHEMBL11713473 | 0.79 | NPC1 (0.66) | KMT2AMEN1USP2KEAP1NFE2L2 | |
| SCHEMBL11713604 | 0.79 | KMT2A (0.51) | KMT2AMEN1USP2KEAP1NFE2L2 | |
| SCHEMBL11712461 | 0.77 | PTGS1 (0.56) | KMT2AMEN1USP2KEAP1NFE2L2 | |
| SCHEMBL11714586 | 0.77 | KMT2A (0.48) | KMT2AMEN1NPC1RAB9AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4055565-A | Optical brightening agents of naphthalimide derivatives | SUMITOMO CHEMICAL COMPANY, LIMITED (JA) | 1977-10-25 | — | — | US | disclosed |