Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | AR | P10275 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11712262 | 0.83 | ALDH1A1 (0.40) | KMT2ANPC1MEN1ALDH1A1KDM4E | |
| SCHEMBL15704592 | 0.80 | ALDH1A1 (0.53) | KMT2ANPC1MEN1ALDH1A1KDM4E | |
| SCHEMBL11708385 | 0.76 | CYP2A6 (0.43) | KMT2AMEN1ALDH1A1KDM4ETSHR | |
| SCHEMBL11710914 | 0.75 | KMT2A (0.42) | KMT2ANPC1MEN1ALDH1A1KDM4E | |
| SCHEMBL11712011 | 0.73 | MAPT (0.42) | KMT2ANPC1MEN1ALDH1A1KDM4E | |
| SCHEMBL28938789 | 0.70 | PDGFRB (0.53) | KMT2ANPC1MEN1ALDH1A1KDM4E | |
| SCHEMBL10939480 | 0.68 | KDM4E (0.57) | KMT2AMEN1ALDH1A1KDM4ETSHR | |
| SCHEMBL18374938 | 0.67 | LMNA (0.52) | NPC1ALDH1A1KDM4ETSHRHSD17B10 | |
| SCHEMBL9206031 | 0.67 | CTSV (0.47) | KMT2ANPC1MEN1MAPTRAB9A | |
| SCHEMBL5361818 | 0.66 | DAO (0.53) | KMT2AMEN1ALDH1A1KDM4ETSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4053624-A | HYPOGLYCEMIC AGENTS | BOEHRINGER MANNHEIM GMBH (DT) | 1977-10-11 | — | — | US | claimed |
| US-4053624-A | HYPOGLYCEMIC AGENTS | BOEHRINGER MANNHEIM GMBH (DT) | 1977-10-11 | — | — | US | disclosed |