Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11712375 | 0.84 | ALDH1A1 (0.48) | POLBCYP1A2CYP3A4ALDH1A1KDM4E | |
| SCHEMBL10563723 | 0.82 | CYP1A2 (0.37) | POLBCYP1A2CYP3A4ALDH1A1KDM4E | |
| SCHEMBL11717549 | 0.81 | ALDH1A1 (0.42) | POLBALDH1A1KDM4EMAPTLMNA | |
| SCHEMBL11717192 | 0.81 | POLB (0.39) | POLBALDH1A1KDM4EMAPTNPC1 | |
| SCHEMBL11716645 | 0.79 | POLB (0.67) | POLBCYP1A2ALDH1A1KDM4EMAPT | |
| SCHEMBL11606834 | 0.77 | ALDH1A1 (0.60) | POLBCYP1A2CYP3A4ALDH1A1KDM4E | |
| SCHEMBL8536659 | 0.73 | HPGD (0.58) | POLBCYP1A2CYP3A4ALDH1A1KDM4E | |
| SCHEMBL7023893 | 0.71 | POLB (0.34) | POLB | |
| SCHEMBL9802279 | 0.70 | POLB (0.39) | POLBCYP1A2CYP3A4ALDH1A1KDM4E | |
| SCHEMBL11721083 | 0.70 | ALDH1A1 (0.39) | POLBALDH1A1KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4036632-A | CONTROLLING WEEDS USING 3-METHYLTHIO-4-AMINO-6-BUTYL-1,2,4 TRIAZINE-5-ONE | BAYER AKTIENGESELLSCHAFT (DT) | 1977-07-19 | — | — | US | disclosed |
| US-3966715-A | 1,2,4-TRIAZINE-5-ONES | BAYER AKTIENGESELLSCHAFT (DT) | 1976-06-29 | — | — | US | disclosed |