Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | NPC1 | O15118 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11703768 | 0.81 | POLB (0.46) | POLBALDH1A1SMN1; SMN2KDM4EMAPT | |
| SCHEMBL9802350 | 0.79 | ALDH1A1 (0.43) | POLBALDH1A1KDM4EMAPTNPC1 | |
| SCHEMBL9802500 | 0.76 | — | — | |
| SCHEMBL9802010 | 0.73 | — | — | |
| SCHEMBL9802450 | 0.73 | ALDH1A1 (0.39) | POLBALDH1A1KDM4EMAPT | |
| SCHEMBL10599397 | 0.71 | POLB (0.65) | POLBALDH1A1SMN1; SMN2KDM4EMAPT | |
| SCHEMBL11716596 | 0.70 | POLB (0.42) | POLBALDH1A1SMN1; SMN2KDM4EMAPT | |
| SCHEMBL11716000 | 0.70 | POLB (0.42) | POLBALDH1A1SMN1; SMN2KDM4EMAPT | |
| SCHEMBL9802250 | 0.70 | ALDH1A1 (0.36) | POLBALDH1A1SMN1; SMN2KDM4EMAPT | |
| SCHEMBL11718518 | 0.68 | POLB (0.41) | POLBALDH1A1SMN1; SMN2KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5076833-A | HERBICIDAL AND PLANT GROWTH-REGULATING 6-(PENT-3-YL)-1,2,4-TRIAZIN-5(4H)-ONES | BAYER AKTIENGESELLSCHAFT (DE) | 1991-12-31 | — | — | US | disclosed |
| EP-0399310-A1 | 6-(Pent-3-yl)-1,2,4-triazin-5-(4H)-ones, process for their preparation and their use as herbicides and plant growth regulators | BAYER AG (DE) | 1990-11-28 | — | — | EP | disclosed |