SCHEMBL117174

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL117169	0.83	NPC1 (0.44)	MEN1KMT2AALDH1A1KDM4EHPGD
	SCHEMBL31339992	0.82	TSPO (0.59)	MEN1KMT2AALDH1A1KDM4EGLA
	SCHEMBL8470659	0.82	TSPO (0.59)	MEN1KMT2AALDH1A1KDM4ECYP1A2
	SCHEMBL3590415	0.82	TSPO (0.59)	MEN1KMT2AALDH1A1KDM4EGLA
	SCHEMBL10985563	0.79	KDM4E (0.48)	MEN1KMT2AALDH1A1KDM4ECYP1A2
	SCHEMBL2139928	0.79	TSPO (0.59)	MEN1KMT2AALDH1A1TSPOCYP3A4
	SCHEMBL10988916	0.79	TSPO (0.48)	MEN1KMT2AALDH1A1TSPOCYP3A4
	SCHEMBL319496	0.78	MGAM (0.44)	ADORA2ACSNK2A2CSNK2BKDM4ETSHR
	SCHEMBL10992082	0.77	GRM2 (0.59)	ADORA2A
	SCHEMBL10995233	0.77	ADORA2A (0.52)	ADORA2ACSNK2A2CSNK2BDHODH

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.