Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | BCL2 | P10415 | 1/20 | 0.37 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 3/20 | 0.36 |
| ▸ | LYN | P07948 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | AR | P10275 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11714786 | 0.87 | MEN1 (0.41) | ALDH1A1GAAKMT2ATDP1NPSR1 | |
| SCHEMBL11716560 | 0.87 | ADORA2A (0.38) | — | |
| SCHEMBL11719593 | 0.82 | MAPT (0.38) | ALDH1A1GAARAB9ASMN1; SMN2NPC1 | |
| SCHEMBL11710405 | 0.80 | ALDH1A1 (0.40) | ALDH1A1GAAKMT2ATDP1RAB9A | |
| SCHEMBL11717845 | 0.79 | BCL2 (0.54) | ALDH1A1GAAKMT2ATDP1RAB9A | |
| SCHEMBL11714311 | 0.78 | PRKCA (0.39) | ALDH1A1GAAKMT2ATDP1RAB9A | |
| SCHEMBL11718390 | 0.73 | MEN1 (0.40) | ALDH1A1GAAKMT2ARAB9AL3MBTL1 | |
| SCHEMBL11709879 | 0.72 | CDC25A (0.43) | ALDH1A1GAAKMT2ATDP1L3MBTL1 | |
| SCHEMBL11714581 | 0.70 | GRM5 (0.40) | RAB9AL3MBTL1SMN1; SMN2NPC1MAPT | |
| SCHEMBL9127700 | 0.68 | PRKCA (0.41) | ALDH1A1KMT2ATDP1NPSR1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4055565-A | Optical brightening agents of naphthalimide derivatives | SUMITOMO CHEMICAL COMPANY, LIMITED (JA) | 1977-10-25 | — | — | US | disclosed |