Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | RHEB | Q15382 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 5/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | APEX1 | P27695 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | BRD4 | O60885 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | BRDT | Q58F21 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11716560 | 0.89 | ADORA2A (0.38) | RHEBBRD4CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL11714786 | 0.87 | MEN1 (0.41) | ALDH1A1LMNASMN1; SMN2HPGDKMT2A | |
| SCHEMBL11719593 | 0.87 | MAPT (0.38) | ALDH1A1LMNASMN1; SMN2HPGDMAPT | |
| SCHEMBL11717840 | 0.80 | ALDH1A1 (0.46) | ALDH1A1LMNASMN1; SMN2KMT2AMAPT | |
| SCHEMBL9127700 | 0.75 | PRKCA (0.41) | ALDH1A1LMNASMN1; SMN2HPGDKMT2A | |
| SCHEMBL11710408 | 0.75 | MCL1 (0.47) | ALDH1A1LMNASMN1; SMN2HPGDKMT2A | |
| SCHEMBL11709879 | 0.74 | CDC25A (0.43) | ALDH1A1LMNAKMT2AMAPTTDP1 | |
| SCHEMBL11718390 | 0.72 | MEN1 (0.40) | ALDH1A1SMN1; SMN2HPGDKMT2AMAPT | |
| SCHEMBL11714581 | 0.72 | GRM5 (0.40) | SMN1; SMN2MAPTHTTNPC1RAB9A | |
| SCHEMBL11714387 | 0.70 | RAB9A (0.39) | ALDH1A1LMNASMN1; SMN2HPGDKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4055565-A | Optical brightening agents of naphthalimide derivatives | SUMITOMO CHEMICAL COMPANY, LIMITED (JA) | 1977-10-25 | — | — | US | disclosed |