SCHEMBL11718005

SCHEMBL11718005

CN(C)C(=S)NC(=S)N(C)N(C)C

nearest known ligand 0.36

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
PKM P14618 1/20 0.35
ALDH1A1 P00352 2/20 0.34
TAS2R38 P59533 1/20 0.33
CA12 O43570 2/20 0.32
CA1 P00915 2/20 0.32
CA2 P00918 2/20 0.32
CA9 Q16790 2/20 0.32
TP53 P04637 1/20 0.30
HPGD P15428 1/20 0.30
ALOX15 P16050 1/20 0.30
ALOX12 P18054 1/20 0.30
MAPK1 P28482 1/20 0.30
HIF1A Q16665 1/20 0.30
HSD17B10 Q99714 1/20 0.30
TDP1 Q9NUW8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11626922 0.85 TAS2R38 (0.44) PKMALDH1A1TAS2R38CA12CA1
Acetone SCHEMBL11622837 0.74 ALDH1A1 (0.44) PKMALDH1A1TAS2R38CA12CA1
SCHEMBL3079814 0.69
SCHEMBL11715116 0.67 CA2 (0.35) ALDH1A1TAS2R38CA12CA1CA2
SCHEMBL10866287 0.67
SCHEMBL728475 0.67 ALDH1A1 (0.34) PKMALDH1A1TAS2R38CA12CA1
SCHEMBL11718188 0.65 CA2 (0.34) ALDH1A1CA12CA1CA2CA9
SCHEMBL11715828 0.65 ALDH1A1 (0.31) ALDH1A1
SCHEMBL3071064 0.65
SCHEMBL10867061 0.63 ALDH1A1 (0.42) PKMALDH1A1TAS2R38HPGDALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4010199-A Miticidal dithiobiurets E. I. DU PONT DE NEMOURS AND COMPANY (US) 1977-03-01 US disclosed