Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11721401 | 0.79 | HSD11B1 (0.34) | TSHR | |
| SCHEMBL9214746 | 0.78 | ALDH1A1 (0.32) | ALDH1A1TDP1 | |
| SCHEMBL11000648 | 0.70 | TSHR (0.38) | TSHR | |
| SCHEMBL10999204 | 0.70 | TSHR (0.43) | TSHRMAPT | |
| SCHEMBL10999767 | 0.70 | TSHR (0.48) | TSHRMAPT | |
| SCHEMBL10999433 | 0.69 | TSHR (0.46) | TSHRALDH1A1MAPT | |
| SCHEMBL11149598 | 0.69 | TSHR (0.41) | TSHRMAPT | |
| SCHEMBL3915320 | 0.68 | CYP1A2 (0.50) | TSHRCYP19A1ALDH1A1MAPT | |
| SCHEMBL11000440 | 0.68 | TSHR (0.45) | TSHRALDH1A1MAPT | |
| SCHEMBL13976239 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4064258-A | Thiazole cardiovascular agents | SYNTEX (U.S.A.) INC. (US) | 1977-12-20 | — | — | US | disclosed |