Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11719604 | 0.78 | TSHR (0.36) | ALDH1A1TDP1 | |
| SCHEMBL24300145 | 0.76 | ALDH1A1 (0.32) | ALDH1A1TDP1 | |
| SCHEMBL24300140 | 0.73 | ALDH1A1 (0.50) | ALDH1A1TDP1 | |
| SCHEMBL24300508 | 0.73 | ALDH1A1 (0.50) | ALDH1A1TDP1 | |
| SCHEMBL937064 | 0.72 | — | — | |
| SCHEMBL24300146 | 0.71 | ALDH1A1 (0.32) | ALDH1A1TDP1 | |
| SCHEMBL9208229 | 0.71 | HSD11B1 (0.37) | ALDH1A1TDP1 | |
| SCHEMBL11342535 | 0.71 | — | — | |
| SCHEMBL13976239 | 0.71 | — | — | |
| SCHEMBL24300644 | 0.70 | ALDH1A1 (0.35) | ALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0500653-A4 | INHIBITORS OF PURINE NUCLEOSIDE PHOSPHORYLASE | BIOCRYST INC (US) | 1995-08-23 | — | — | EP | disclosed |
| EP-0500653-A1 | INHIBITORS OF PURINE NUCLEOSIDE PHOSPHORYLASE | BIOCRYST PHARMACEUTICALS INC. (US) | 1992-09-02 | — | — | EP | disclosed |
| WO-1991006548-A1 | INHIBITORS OF PURINE NUCLEOSIDE PHOSPHORYLASE | BIOCRYST, INC. (US) | 1991-05-16 | — | — | WO | disclosed |
| US-5008265-A | 2-amino-7-(alicyclomethyl)-3H,5H,-pyrrolo[3,2-d]pyrimidin-4-ones and pharmaceutical uses and compositions containing the same | BIOCRYST, INC. (US) | 1991-04-16 | — | — | US | disclosed |