Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 7/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 4/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.35 |
| ▸ | FDPS | P14324 | 2/20 | 0.34 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.32 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.32 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.32 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18613982 | 0.93 | LMNA (0.39) | CA2CA1FDPSHSPD1BLM | |
| SCHEMBL18301373 | 0.91 | LMNA (0.43) | CA2DNM1FDPSHSPD1BLM | |
| SCHEMBL11067651 | 0.91 | LMNA (0.43) | CA2DNM1FDPSHSPD1BLM | |
| SCHEMBL18613882 | 0.84 | CA1 (0.34) | CA2CA1TDP1 | |
| SCHEMBL5614423 | 0.81 | CA2 (0.35) | CA2MAPK1CA1ALDH1A1DNM1 | |
| SCHEMBL14142959 | 0.81 | CA2 (0.45) | CA2MAPK1CA1FDPSSLC1A3 | |
| SCHEMBL16393984 | 0.80 | — | — | |
| SCHEMBL359407 | 0.79 | ALDH1A1 (0.47) | CA2MAPK1CA1ALDH1A1TDP1 | |
| SCHEMBL5315634 | 0.78 | LMNA (0.40) | BLMLMNA | |
| SCHEMBL3286726 | 0.78 | CA2 (0.33) | CA2MAPK1CA1ALDH1A1DNM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017044889-A1 | LRH-1 MODULATORS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2017-03-16 | — | — | WO | disclosed |
| US-4036794-A | SUSPENSION POLYMERIZATION, BLOWING AGENTS, STABILIZERS | BASF AKTIENGESELLSCHAFT (DT) | 1977-07-19 | — | — | US | disclosed |