Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 20/20 | 0.58 |
| ▸ | DDB1 | Q16531 | 6/20 | 0.58 |
| ▸ | IKZF3 | Q9UKT9 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16798767 | 1.00 | CRBN (0.58) | CRBNDDB1IKZF3 | |
| SCHEMBL17336169 | 0.83 | CRBN (0.64) | CRBNDDB1IKZF3 | |
| SCHEMBL19359394 | 0.83 | CRBN (0.64) | CRBNDDB1IKZF3 | |
| SCHEMBL20234394 | 0.83 | CRBN (0.56) | CRBNDDB1IKZF3 | |
| SCHEMBL20463081 | 0.83 | CRBN (0.52) | CRBNDDB1IKZF3 | |
| SCHEMBL19370678 | 0.82 | CRBN (0.50) | CRBNDDB1IKZF3 | |
| SCHEMBL22527248 | 0.82 | CRBN (0.55) | CRBNDDB1IKZF3 | |
| SCHEMBL13174886 | 0.82 | CRBN (0.51) | CRBNDDB1IKZF3 | |
| SCHEMBL22151716 | 0.82 | CRBN (0.51) | CRBNDDB1IKZF3 | |
| SCHEMBL11720185 | 0.81 | GAA (0.42) | CRBNDDB1IKZF3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8481558-B2 | Compounds to inhibit or augment an inflammatory response | CAMBRIDGE ENTERPRISE LIMITED (GB) | 2013-07-09 | — | — | US | disclosed |
| US-20120065401-A1 | METHODS TO INHIBIT OR AUGMENT AN INFLAMMATORY RESPONSE | CAMBRIDGE ENTERPRISE LIMITED (GB) | 2012-03-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120065401-A1 | METHODS TO INHIBIT OR AUGMENT AN INFLAMMATORY RESPONSE | CCL2, CCL5, CCL11 | CRBN 3483/4885DDB1 1092/4885IKZF3 1648/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.