Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APOL1 | O14791 | 2/20 | 0.40 |
| ▸ | NAAA | Q02083 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | CRBN | Q96SW2 | 5/20 | 0.38 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.36 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.36 |
| ▸ | DDB1 | Q16531 | 2/20 | 0.36 |
| ▸ | CCR2 | P41597 | 1/20 | 0.35 |
| ▸ | MAP3K14 | Q99558 | 1/20 | 0.35 |
| ▸ | IKZF3 | Q9UKT9 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19370694 | 0.83 | CRBN (0.54) | CRBNDDB1IKZF3 | |
| SCHEMBL28659413 | 0.82 | APOL1 (0.40) | APOL1NAAAGAATSHRCRBN | |
| SCHEMBL26317916 | 0.81 | NAAA (0.53) | APOL1NAAACRBNCCR2 | |
| SCHEMBL11132566 | 0.79 | GAA (0.42) | APOL1GAATSHRCRBNDDB1 | |
| SCHEMBL11720185 | 0.79 | GAA (0.42) | APOL1GAATSHRCRBNDDB1 | |
| SCHEMBL19359384 | 0.77 | CRBN (0.42) | APOL1GAATSHRCRBNDDB1 | |
| SCHEMBL19359454 | 0.77 | CRBN (0.42) | APOL1GAATSHRCRBNDDB1 | |
| SCHEMBL19359238 | 0.77 | CRBN (0.42) | APOL1GAATSHRCRBNDDB1 | |
| SCHEMBL22446315 | 0.73 | GAA (0.44) | GAATSHRCRBNDDB1MAP3K14 | |
| SCHEMBL23513495 | 0.72 | GAA (0.59) | GAATSHRCRBNDDB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1201664-B1 | BENZIMIDAZOLE COMPOUNDS AND DRUGS CONTAINING THE SAME | FUJI PHOTO FILM CO LTD (JP) | 2004-09-08 | — | — | EP | disclosed |
| US-6593323-B1 | Benzimidazole compound inhibitory action of forming of macrophages and is useful as an active ingredient of a medicament for preventive and/or therapeutic treatment of arteriosclerosis, which is represented by the formula (I): | FUJI PHOTO FILM CO., LTD. (JP) | 2003-07-15 | — | — | US | disclosed |
| EP-1201664-A1 | BENZIMIDAZOLE COMPOUNDS AND DRUGS CONTAINING THE SAME | FUJI PHOTO FILM CO., LTD. (JP) | 2002-05-02 | — | — | EP | disclosed |