Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 3/20 | 0.69 |
| ▸ | RORA | P35398 | 1/20 | 0.69 |
| ▸ | RORC | P51449 | 1/20 | 0.69 |
| ▸ | RORB | Q92753 | 1/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.66 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.60 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.60 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.60 |
| ▸ | HTT | P42858 | 3/20 | 0.59 |
| ▸ | LMNA | P02545 | 2/20 | 0.59 |
| ▸ | HPGD | P15428 | 2/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.56 |
| ▸ | NPY5R | Q15761 | 3/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | MITF | O75030 | 1/20 | 0.54 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14560568 | 0.87 | TDP1 (0.64) | PGRRORARORCRORBALDH1A1 | |
| SCHEMBL6169717 | 0.84 | KDM4E (0.69) | PGRRORARORCRORBALDH1A1 | |
| SCHEMBL6168093 | 0.84 | DPP4 (0.59) | PGRRORARORCRORBALDH1A1 | |
| SCHEMBL6171511 | 0.84 | KDM4E (0.69) | PGRRORARORCRORBALDH1A1 | |
| SCHEMBL29963695 | 0.83 | ALDH1A1 (0.75) | ALDH1A1KDM4ERCE1HTTLMNA | |
| SCHEMBL151563 | 0.83 | ALDH1A1 (0.75) | ALDH1A1KDM4ERCE1HTTLMNA | |
| SCHEMBL29360167 | 0.83 | ALDH1A1 (0.75) | ALDH1A1KDM4ERCE1HTTLMNA | |
| SCHEMBL30485670 | 0.82 | PGR (0.68) | PGRRORARORCRORBALDH1A1 | |
| SCHEMBL6362477 | 0.82 | PGR (0.68) | PGRRORARORCRORBALDH1A1 | |
| SCHEMBL14141960 | 0.82 | RORA (1.00) | PGRRORARORCRORBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11713319-B2 | Compounds having valerolactam structures | MERCK PATENT GMBH (DE) | 2023-08-01 | — | — | US | disclosed |
| US-9193749-B2 | Dibenzo[b,f][1,4]oxazepin-11-yl-N-hydroxybenzamides as HDAC inhibitors | FORUM PHARMACEUTICALS, INC. (US) | 2015-11-24 | — | — | US | disclosed |
| US-20140011988-A1 | Dibenzo[B,F][1,4]Oxazepin-11-yl-N-Hydroxybenzamides as HDAC Inhibitors | FMR LLC | 2014-01-09 | — | — | US | disclosed |
| US-4020073-A | Process for O-acylating thallus salts of 2-pyridone | TAYLOR EDWARD C | 1977-04-26 | — | — | US | disclosed |
| US-3947488-A | O-Acylation using organothallium compounds | TAYLOR EDWARD C | 1976-03-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11713319-B2 | Compounds having valerolactam structures | ACE, CYP3A4, CYP2D6 | PGR 818/4885RORA 301/4885RORC 173/4885 |
| US-20140011988-A1 | Dibenzo[B,F][1,4]Oxazepin-11-yl-N-Hydroxybenzamides as HDAC Inhibitors | HDAC1, HDAC2, HDAC4 | PGR 4391/4885RORA 621/4885RORC 663/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.