Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHBP | P24387 | 1/20 | 0.43 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | KCNMA1 | Q12791 | 3/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11720856 | 0.84 | KCNMA1 (0.49) | CRHBPCRHR2TDP1KCNMA1USP2 | |
| SCHEMBL10721057 | 0.77 | CASP6 (0.50) | HPGDPOLBALDH1A1NPC1RAB9A | |
| SCHEMBL11714127 | 0.76 | AURKB (0.43) | TDP1L3MBTL1HPGDUSP2POLB | |
| SCHEMBL11437898 | 0.74 | HPGD (0.59) | TDP1HPGDUSP2POLBALDH1A1 | |
| SCHEMBL11439150 | 0.74 | MAPT (0.52) | TDP1HPGDUSP2POLBALDH1A1 | |
| SCHEMBL16583563 | 0.74 | TDP1 (0.60) | CRHBPCRHR2TDP1L3MBTL1HPGD | |
| SCHEMBL11437902 | 0.72 | KCNMA1 (0.51) | CRHBPCRHR2TDP1KCNMA1USP2 | |
| SCHEMBL11426047 | 0.72 | HPGD (0.62) | TDP1HPGDUSP2POLBALDH1A1 | |
| SCHEMBL11439152 | 0.72 | KCNMA1 (0.48) | CRHBPCRHR2TDP1HPGDKCNMA1 | |
| SCHEMBL11423955 | 0.72 | HPGD (0.52) | TDP1HPGDUSP2POLBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4018764-A | IMMUNOLOGY, ANTIBODY INHIBITORS | AMERICAN CYANAMID COMPANY (US) | 1977-04-19 | — | — | US | disclosed |