Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | OPRK1 | P41145 | 4/20 | 0.46 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.46 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.46 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.44 |
| ▸ | USP2 | O75604 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11723365 | 1.00 | ALDH1A1 (0.49) | ALDH1A1OPRK1OPRM1OPRD1PTGER4 | |
| SCHEMBL11723581 | 0.99 | ALDH1A1 (0.48) | ALDH1A1OPRK1OPRM1OPRD1PTGER4 | |
| SCHEMBL11726427 | 0.92 | KDM4E (0.42) | ALDH1A1OPRK1OPRM1OPRD1PTGER4 | |
| SCHEMBL11724257 | 0.91 | LMNA (0.54) | ALDH1A1PTGER4TSHRKDM4ETP53 | |
| SCHEMBL11729078 | 0.90 | KDM4E (0.53) | ALDH1A1OPRK1OPRM1OPRD1PTGER4 | |
| SCHEMBL11721756 | 0.90 | ALDH1A1 (0.42) | ALDH1A1OPRK1OPRM1OPRD1PTGER4 | |
| SCHEMBL11723851 | 0.90 | ALDH1A1 (0.51) | ALDH1A1OPRK1OPRM1OPRD1CYP2D6 | |
| SCHEMBL11717303 | 0.90 | ALDH1A1 (0.51) | ALDH1A1OPRK1OPRM1OPRD1CYP2D6 | |
| SCHEMBL11724229 | 0.89 | ALDH1A1 (0.49) | ALDH1A1OPRK1OPRM1OPRD1USP2 | |
| SCHEMBL11723912 | 0.85 | HRH1 (0.48) | ALDH1A1OPRK1OPRM1OPRD1PTGER4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4053472-A | MICROBIOCIDES | SCHERING AKTIENGESELLSCHAFT (DT) | 1977-10-11 | — | — | US | disclosed |