Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 3/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | HRH1 | P35367 | 2/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 4/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.41 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.41 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.39 |
| ▸ | MTOR | P42345 | 1/20 | 0.39 |
| ▸ | IRAK1 | P51617 | 1/20 | 0.39 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
| ▸ | CASP7 | P55210 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11726427 | 0.92 | KDM4E (0.42) | KDM4EALDH1A1LMNAOPRK1OPRM1 | |
| SCHEMBL11723581 | 0.91 | ALDH1A1 (0.48) | KDM4ETSHRALDH1A1LMNAMAPK1 | |
| SCHEMBL11720882 | 0.90 | ALDH1A1 (0.49) | KDM4ECYP2C19TSHRALDH1A1LMNA | |
| SCHEMBL11723365 | 0.90 | ALDH1A1 (0.49) | KDM4ECYP2C19TSHRALDH1A1LMNA | |
| SCHEMBL11724257 | 0.89 | LMNA (0.54) | KDM4ETSHRPOLBALDH1A1LMNA | |
| SCHEMBL11721756 | 0.89 | ALDH1A1 (0.42) | KDM4ETSHRALDH1A1LMNAMAPK1 | |
| SCHEMBL11723912 | 0.87 | HRH1 (0.48) | KDM4EALDH1A1LMNAHRH1OPRK1 | |
| SCHEMBL11725228 | 0.85 | KDM4E (0.40) | KDM4EALDH1A1HRH1 | |
| SCHEMBL11722066 | 0.82 | LMNA (0.43) | KDM4ECYP2C19TSHRALDH1A1LMNA | |
| SCHEMBL11724229 | 0.81 | ALDH1A1 (0.49) | KDM4ETSHRALDH1A1LMNAMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4053472-A | MICROBIOCIDES | SCHERING AKTIENGESELLSCHAFT (DT) | 1977-10-11 | — | — | US | disclosed |