Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 4/20 | 0.51 |
| ▸ | PPARA | Q07869 | 2/20 | 0.49 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | HTR2A | P28223 | 1/20 | 0.49 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | PPID | Q08752 | 2/20 | 0.43 |
| ▸ | FBP1 | P09467 | 1/20 | 0.43 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | PPIB | P23284 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11716391 | 0.89 | PPARA (0.65) | POLBPPARAABCB11CYP1A2CYP3A4 | |
| SCHEMBL11714161 | 0.85 | ALDH1A1 (0.44) | POLBPPARAABCB11CYP1A2CYP3A4 | |
| SCHEMBL11718681 | 0.84 | PPARA (0.59) | POLBPPARAABCB11CYP1A2CYP3A4 | |
| SCHEMBL22221502 | 0.83 | PPARA (0.58) | POLBPPARAABCB11CYP1A2CYP3A4 | |
| SCHEMBL11711211 | 0.83 | POLB (0.41) | POLBPPARAABCB11CYP1A2CYP3A4 | |
| SCHEMBL11714411 | 0.80 | ALDH1A1 (0.41) | POLBPPARAABCB11CYP1A2CYP3A4 | |
| SCHEMBL11717120 | 0.78 | MMP13 (0.48) | CYP1A2CYP3A4TSHRALDH1A1HTT | |
| SCHEMBL3903999 | 0.78 | PPARA (0.76) | PPARAABCB11CYP1A2CYP3A4TSHR | |
| SCHEMBL25442329 | 0.78 | LMNA (0.44) | POLBPPARAABCB11CYP1A2CYP3A4 | |
| SCHEMBL13915663 | 0.76 | PPID (0.48) | POLBCYP1A2CYP3A4SMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4033974-A | Pyridylmethyl esters of N-(phenoxyalkanoyl)peptide derivatives | AMERICAN HOME PRODUCTS CORPORATION (US) | 1977-07-05 | — | — | US | disclosed |
| US-3956484-A | Pyridylmethyl esters of N-(phenoxyalkanoyl)peptide derivatives for therepeutic use | AMERICAN HOME PRODUCTS CORPORATION (US) | 1976-05-11 | — | — | US | disclosed |