Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | ESR1 | P03372 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.38 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.38 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.38 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.38 |
| ▸ | PLK1 | P53350 | 1/20 | 0.38 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | ATF1 | P18846 | 2/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11723166 | 0.87 | TRPV1 (0.44) | FAAHAKR1C3AKR1C2TRPV1 | |
| SCHEMBL11722855 | 0.83 | AKR1C3 (0.48) | ALDH1A1ESR1NPC1MAPTRAB9A | |
| SCHEMBL11719797 | 0.82 | AKR1C3 (0.45) | ALDH1A1NPC1RAB9AAKR1C3AKR1C2 | |
| SCHEMBL11720900 | 0.82 | THRA (0.41) | ALDH1A1NPC1MAPTRAB9ATSHR | |
| SCHEMBL11723982 | 0.81 | APP (0.42) | ALDH1A1NPC1RAB9ASMN1; SMN2TSHR | |
| SCHEMBL11725310 | 0.81 | LMNA (0.37) | ALDH1A1TSHRLMNA | |
| SCHEMBL11459202 | 0.80 | PDE2A (0.41) | MAPTAKR1C3AKR1C2SMN1; SMN2LMNA | |
| SCHEMBL11719717 | 0.79 | SMN1; SMN2 (0.41) | ALDH1A1ESR1NPC1MAPTRAB9A | |
| SCHEMBL11717864 | 0.79 | AKR1C3 (0.40) | NPC1RAB9AAKR1C3AKR1C2AKR1C1 | |
| SCHEMBL11726834 | 0.78 | ALDH1A1 (0.44) | ALDH1A1ESR1NPC1RAB9AAKR1C3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4048330-A | Compositions containing 2-(6'-substituted-2'-naphthyl)acetic acid esters used for treating inflammation, pain or pyrexia | SYNTEX CORPORATION (US) | 1977-09-13 | — | — | US | disclosed |
| US-4009197-A | 2-(6-Substituted-2'-naphthyl) acetic acid derivatives and the salts and esters thereof | SYNTEX CORPORATION (PM) | 1977-02-22 | — | — | US | disclosed |