Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1 | Q05193 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.30 |
| ▸ | CA12 | O43570 | 1/20 | 0.30 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA9 | Q16790 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17553066 | 0.81 | DNM1 (0.32) | DNM1ALDH1A1ALDH2CA12CA1 | |
| SCHEMBL9950371 | 0.81 | TSHR (0.32) | LMNATSHR | |
| SCHEMBL20536992 | 0.80 | — | — | |
| SCHEMBL20537191 | 0.78 | — | — | |
| SCHEMBL26000130 | 0.78 | ALDH1A1 (0.38) | ALDH1A1 | |
| SCHEMBL19773409 | 0.77 | — | — | |
| SCHEMBL19712171 | 0.77 | — | — | |
| SCHEMBL17553075 | 0.77 | TSHR (0.35) | ALDH1A1TSHR | |
| SCHEMBL20536699 | 0.77 | — | — | |
| SCHEMBL29142967 | 0.75 | DNM1 (0.33) | DNM1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4029693-A | HYPOTENSIVES, ANTISECRETORY, ANTIFERTILITY | THE UPJOHN COMPANY (US) | 1977-06-14 | — | — | US | disclosed |