Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | MPO | P05164 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | KDM5A | P29375 | 1/20 | 0.50 |
| ▸ | BLM | P54132 | 1/20 | 0.50 |
| ▸ | GFER | P55789 | 1/20 | 0.50 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.50 |
| ▸ | IDO1 | P14902 | 2/20 | 0.48 |
| ▸ | MIF | P14174 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 3/20 | 0.45 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.45 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.45 |
| ▸ | TPSD1 | Q9BZJ3 | 1/20 | 0.45 |
| ▸ | TPSG1 | Q9NRR2 | 1/20 | 0.45 |
| ▸ | CA12 | O43570 | 2/20 | 0.45 |
| ▸ | CA1 | P00915 | 2/20 | 0.45 |
| ▸ | CA9 | Q16790 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL156297 | 0.84 | CA12 (0.62) | KMT2ALMNACA2CA12CA1 | |
| Water SCHEMBL30097036 | 0.82 | CA12 (0.60) | KMT2ALMNACA2CA12CA1 | |
| Hydrochloric Acid SCHEMBL7026708 | 0.82 | CA12 (0.60) | KMT2ALMNACA2CA12CA1 | |
| SCHEMBL669426 | 0.82 | ALDH1A1 (0.65) | MEN1KMT2AIDO1MIFCA2 | |
| Hydrazine SCHEMBL28937719 | 0.81 | CA12 (0.58) | KMT2ALMNACA2CA12CA1 | |
| SCHEMBL28254012 | 0.80 | ALDH1A1 (0.41) | MEN1KMT2ALMNACA2PRSS1 | |
| SCHEMBL14008716 | 0.80 | TPSAB1 (0.40) | LMNACA2PRSS1TPSAB1TPSD1 | |
| SCHEMBL4416640 | 0.80 | SMN1; SMN2 (0.61) | MEN1KMT2ALMNAALDH1A1 | |
| SCHEMBL452919 | 0.80 | MEN1 (0.55) | MEN1KMT2AIDO1MIFLMNA | |
| SCHEMBL452918 | 0.80 | MEN1 (0.55) | MEN1KMT2AIDO1MIFLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4021387-A | PARASITICIDES, ANAPHYLAXIS, BRONCHIAL ASTHMA | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 1977-05-03 | — | — | US | disclosed |