SCHEMBL28254012

SCHEMBL28254012

C[N+](C)(C)c1ccc(COC(=O)NN)cc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.41
AOC3 Q16853 1/20 0.40
TPSAB1 Q15661 3/20 0.40
PRSS1 P07477 2/20 0.40
TPSD1 Q9BZJ3 1/20 0.40
TPSG1 Q9NRR2 1/20 0.40
PLG P00747 1/20 0.40
CA12 O43570 2/20 0.40
CA1 P00915 2/20 0.40
CA2 P00918 2/20 0.40
CA9 Q16790 2/20 0.40
NPC1 O15118 1/20 0.39
RAB9A P51151 1/20 0.39
MAPT P10636 2/20 0.38
MAPK1 P28482 1/20 0.38
HTT P42858 1/20 0.38
SMN1; SMN2 Q16637 2/20 0.38
MEN1 O00255 1/20 0.38
KMT2A Q03164 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL112716 0.81 ACHE (0.41) ALDH1A1CA1CA2MAPK1MEN1
SCHEMBL11722992 0.80 MEN1 (0.55) ALDH1A1TPSAB1PRSS1TPSD1TPSG1
SCHEMBL28959269 0.80 ALDH1A1 (0.42) ALDH1A1MAPTMAPK1MEN1KMT2A
SCHEMBL669426 0.78 ALDH1A1 (0.65) ALDH1A1CA1CA2NPC1RAB9A
SCHEMBL156297 0.77 CA12 (0.62) ALDH1A1CA12CA1CA2CA9
SCHEMBL4416640 0.77 SMN1; SMN2 (0.61) ALDH1A1NPC1RAB9AMAPTSMN1; SMN2
Hydrochloric Acid SCHEMBL7026708 0.75 CA12 (0.60) ALDH1A1CA12CA1CA2CA9
Water SCHEMBL30097036 0.75 CA12 (0.60) ALDH1A1CA12CA1CA2CA9
Alcohol SCHEMBL28648245 0.75 CA12 (0.55) ALDH1A1CA12CA1CA2CA9
Hydrazine SCHEMBL28937719 0.74 CA12 (0.58) ALDH1A1CA12CA1CA2CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108778289-A TRITERPENE SAPONIN ANALOGUES 佐剂技术公司 2018-11-09 CN disclosed