Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.45 |
| ▸ | CASP1 | P29466 | 1/20 | 0.45 |
| ▸ | CASP7 | P55210 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | MTOR | P42345 | 1/20 | 0.45 |
| ▸ | IRAK1 | P51617 | 1/20 | 0.45 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | GAA | P10253 | 4/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11722753 | 0.95 | LMNA (0.56) | LMNAHSD17B10CASP1CASP7L3MBTL1 | |
| SCHEMBL11724229 | 0.87 | ALDH1A1 (0.49) | LMNAALDH1A1KDM4EHDAC1HDAC8 | |
| SCHEMBL11722066 | 0.86 | LMNA (0.43) | LMNAHSD17B10CASP1CASP7L3MBTL1 | |
| SCHEMBL11723851 | 0.86 | ALDH1A1 (0.51) | LMNACYP2D6CYP2C19ALDH1A1KDM4E | |
| SCHEMBL11717303 | 0.86 | ALDH1A1 (0.51) | LMNACYP2D6CYP2C19ALDH1A1KDM4E | |
| SCHEMBL11724257 | 0.85 | LMNA (0.54) | LMNAHSD17B10CASP1CASP7L3MBTL1 | |
| SCHEMBL11724092 | 0.84 | ALDH1A1 (0.43) | LMNAMTORIRAK1IRAK4CYP2C19 | |
| SCHEMBL11725269 | 0.81 | KDM4E (0.39) | LMNAMAPTALDH1A1KDM4EGAA | |
| SCHEMBL11725390 | 0.80 | ALDH1A1 (0.52) | LMNAL3MBTL1IRAK1IRAK4MAPT | |
| SCHEMBL11727356 | 0.80 | ALDH1A1 (0.45) | LMNAMAPTALDH1A1HPGDGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4053472-A | MICROBIOCIDES | SCHERING AKTIENGESELLSCHAFT (DT) | 1977-10-11 | — | — | US | claimed |
| US-4053472-A | MICROBIOCIDES | SCHERING AKTIENGESELLSCHAFT (DT) | 1977-10-11 | — | — | US | disclosed |