Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | LTA4H | P09960 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | TEAD3 | Q99594 | 1/20 | 0.37 |
| ▸ | HRH1 | P35367 | 2/20 | 0.37 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.37 |
| ▸ | ESR1 | P03372 | 1/20 | 0.37 |
| ▸ | DRD2 | P14416 | 1/20 | 0.37 |
| ▸ | DRD3 | P35462 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11725228 | 0.91 | KDM4E (0.40) | KDM4EALDH1A1HRH1 | |
| SCHEMBL11722066 | 0.86 | LMNA (0.43) | KDM4EALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL11724229 | 0.85 | ALDH1A1 (0.49) | KDM4EALDH1A1LMNA | |
| SCHEMBL11723511 | 0.85 | HRH1 (0.47) | ALDH1A1LMNAHRH1 | |
| SCHEMBL11717303 | 0.84 | ALDH1A1 (0.51) | KDM4EALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL11723851 | 0.84 | ALDH1A1 (0.51) | KDM4EALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL11722753 | 0.83 | LMNA (0.56) | KDM4EALDH1A1MAPTLMNAMEN1 | |
| SCHEMBL11724092 | 0.82 | ALDH1A1 (0.43) | KDM4EALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL11723336 | 0.81 | LMNA (0.50) | KDM4EALDH1A1MAPTLMNAGAA | |
| SCHEMBL11726427 | 0.77 | KDM4E (0.42) | KDM4EALDH1A1MAPTLMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4053472-A | MICROBIOCIDES | SCHERING AKTIENGESELLSCHAFT (DT) | 1977-10-11 | — | — | US | disclosed |