Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.40 |
| ▸ | HRH1 | P35367 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.37 |
| ▸ | HTT | P42858 | 4/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | IDO1 | P14902 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 4/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | CASR | P41180 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11724268 | 0.78 | BRD4 (0.41) | BRD4HRH1KDM4EHTTMEN1 | |
| SCHEMBL11724279 | 0.76 | BRD4 (0.41) | BRD4HRH1KDM4EHTTMEN1 | |
| SCHEMBL11725537 | 0.76 | IRAK4 (0.38) | BRD4KDM4EMAPTRXFP1LMNA | |
| SCHEMBL11720098 | 0.74 | KCNK13 (0.35) | BRD4KDM4EHTTMEN1MAPT | |
| SCHEMBL11724259 | 0.73 | EGFR (0.41) | BRD4HRH1KDM4EMEN1MAPT | |
| SCHEMBL11723310 | 0.72 | GLA (0.46) | BRD4HRH1KDM4EMAPTLMNA | |
| SCHEMBL501463 | 0.70 | HPGD (0.69) | HRH1KDM4ELMNAPKMNPSR1 | |
| SCHEMBL11669289 | 0.69 | KDM4E (0.33) | KDM4ESMN1; SMN2ALDH1A1 | |
| SCHEMBL13587967 | 0.68 | LMNA (0.57) | HRH1KDM4EHTTLMNAPKM | |
| SCHEMBL11669196 | 0.67 | KDM4E (0.42) | KDM4EMAPTKMT2ARXFP1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4053472-A | MICROBIOCIDES | SCHERING AKTIENGESELLSCHAFT (DT) | 1977-10-11 | — | — | US | disclosed |