Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLA | P06280 | 2/20 | 0.51 |
| ▸ | EGFR | P00533 | 10/20 | 0.42 |
| ▸ | ERBB2 | P04626 | 10/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 2/20 | 0.41 |
| ▸ | CA1 | P00915 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | CA9 | Q16790 | 2/20 | 0.41 |
| ▸ | GUSB | P08236 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11725677 | 0.85 | GLA (0.46) | GLAEGFRERBB2ALDH1A1MAPT | |
| SCHEMBL11727261 | 0.84 | LMNA (0.53) | GLAEGFRERBB2ALDH1A1KMT2A | |
| SCHEMBL11726175 | 0.84 | LMNA (0.41) | GLAEGFRERBB2ALDH1A1KMT2A | |
| SCHEMBL11726189 | 0.82 | LMNA (0.41) | GLAEGFRERBB2ALDH1A1MEN1 | |
| SCHEMBL11724706 | 0.78 | GLA (0.51) | GLAEGFRERBB2ALDH1A1MAPT | |
| SCHEMBL11725247 | 0.78 | LMNA (0.39) | GLAALDH1A1KMT2ACA12CA1 | |
| Hydrochloric Acid SCHEMBL11725208 | 0.77 | LMNA (0.38) | GLAALDH1A1KMT2ACA12CA1 | |
| SCHEMBL677158 | 0.76 | GLA (0.78) | GLAEGFRERBB2ALDH1A1MAPT | |
| SCHEMBL11726033 | 0.74 | ALDH1A1 (0.46) | EGFRERBB2ALDH1A1MAPTMEN1 | |
| SCHEMBL11824972 | 0.73 | EGFR (0.58) | GLAEGFRERBB2ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4065567-A | Substituted nitroimidazolyl thiadiazoles and oxadiazoles as antibacterial agents and growth promoting compounds | AMERICAN CYANAMID COMPANY (US) | 1977-12-27 | — | — | US | disclosed |
| US-3991200-A | Substituted nitroimidazolyl thiadiazoles and oxadiazoles as antibacterial agents and growth promoting compounds | AMERICAN CYANAMID COMPANY (US) | 1976-11-09 | — | — | US | disclosed |