Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 5/20 | 0.41 |
| ▸ | CA2 | P00918 | 5/20 | 0.41 |
| ▸ | CA9 | Q16790 | 5/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 4/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | TYMS | P04818 | 1/20 | 0.32 |
| ▸ | EGFR | P00533 | 1/20 | 0.32 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11726189 | 0.91 | LMNA (0.41) | LMNAALDH1A1MAPK1THRBTSHR | |
| SCHEMBL11727261 | 0.88 | LMNA (0.53) | LMNAALDH1A1MAPK1THRBTSHR | |
| SCHEMBL11724718 | 0.84 | GLA (0.51) | ALDH1A1CA1CA2CA9CA12 | |
| SCHEMBL11725247 | 0.84 | LMNA (0.39) | LMNAALDH1A1MAPK1THRBTSHR | |
| Hydrochloric Acid SCHEMBL11725208 | 0.83 | LMNA (0.38) | LMNAALDH1A1MAPK1THRBTSHR | |
| SCHEMBL11726033 | 0.81 | ALDH1A1 (0.46) | LMNAALDH1A1MAPK1THRBTSHR | |
| SCHEMBL11728995 | 0.75 | LMNA (0.39) | LMNAALDH1A1MAPK1THRBTSHR | |
| SCHEMBL11726166 | 0.74 | LMNA (0.41) | LMNAALDH1A1MAPK1THRBTSHR | |
| SCHEMBL11727803 | 0.72 | ALDH1A1 (0.44) | LMNAALDH1A1MAPK1THRBTSHR | |
| SCHEMBL681530 | 0.72 | LMNA (0.73) | LMNAALDH1A1MAPK1THRBTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4065567-A | Substituted nitroimidazolyl thiadiazoles and oxadiazoles as antibacterial agents and growth promoting compounds | AMERICAN CYANAMID COMPANY (US) | 1977-12-27 | — | — | US | disclosed |