Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.62 |
| ▸ | EYA3 | Q99504 | 3/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.58 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.54 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.51 |
| ▸ | CNR2 | P34972 | 6/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.49 |
| ▸ | CNR1 | P21554 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11735403 | 0.89 | L3MBTL1 (0.54) | L3MBTL1EYA3CYP2C19SLC22A12PTPN1 | |
| SCHEMBL11724757 | 0.86 | EYA3 (0.66) | L3MBTL1EYA3CYP2C19SLC22A12PTPN1 | |
| SCHEMBL11672912 | 0.86 | EYA3 (0.66) | L3MBTL1EYA3CYP2C19SLC22A12PTPN1 | |
| SCHEMBL11734608 | 0.85 | L3MBTL1 (0.64) | L3MBTL1EYA3CYP2C19SLC22A12PTPN1 | |
| SCHEMBL11672355 | 0.85 | L3MBTL1 (0.64) | L3MBTL1EYA3CYP2C19SLC22A12PTPN1 | |
| SCHEMBL11673100 | 0.83 | L3MBTL1 (0.62) | L3MBTL1EYA3CYP2C19SLC22A12PTPN1 | |
| SCHEMBL11729109 | 0.83 | L3MBTL1 (0.62) | L3MBTL1EYA3CYP2C19SLC22A12PTPN1 | |
| SCHEMBL11730698 | 0.83 | L3MBTL1 (0.62) | L3MBTL1EYA3CYP2C19SLC22A12PTPN1 | |
| SCHEMBL10674000 | 0.83 | L3MBTL1 (0.51) | L3MBTL1CNR2MEN1ALDH1A1CYP3A4 | |
| SCHEMBL11730706 | 0.81 | EYA3 (0.60) | L3MBTL1EYA3CYP2C19SLC22A12PTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4001426-A | HAVING CORONARY VASODILATOR ACTIVITY | SMITHKLINE CORPORATION (US) | 1977-01-04 | — | — | US | disclosed |