Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | JAK2 | O60674 | 1/20 | 0.40 |
| ▸ | JAK1 | P23458 | 1/20 | 0.40 |
| ▸ | TYK2 | P29597 | 1/20 | 0.40 |
| ▸ | JAK3 | P52333 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.36 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | AGPAT2 | O15120 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11725390 | 0.82 | ALDH1A1 (0.52) | ALDH1A1LMNATHRBTSHRMAPK1 | |
| Hydrochloric Acid SCHEMBL11719065 | 0.73 | CNR2 (0.41) | ALDH1A1LMNATHRBTSHRMAPK1 | |
| SCHEMBL11727356 | 0.71 | ALDH1A1 (0.45) | ALDH1A1LMNATHRBTSHRMAPK1 | |
| SCHEMBL5015559 | 0.70 | KMT2A (0.53) | LMNAJAK2JAK1TYK2JAK3 | |
| SCHEMBL11725307 | 0.70 | POLB (0.46) | ALDH1A1KDM4EKMT2AMEN1HTT | |
| SCHEMBL11725524 | 0.69 | ALDH1A1 (0.47) | ALDH1A1LMNATHRBTSHRMAPK1 | |
| Hydrochloric Acid SCHEMBL11724250 | 0.69 | POLB (0.45) | ALDH1A1KDM4EKMT2AMEN1HTT | |
| SCHEMBL11723310 | 0.69 | GLA (0.46) | ALDH1A1LMNAKDM4EMAPT | |
| SCHEMBL11724229 | 0.68 | ALDH1A1 (0.49) | ALDH1A1LMNATSHRMAPK1KDM4E | |
| SCHEMBL5444693 | 0.68 | LMNA (0.46) | ALDH1A1LMNATHRBTSHRMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4053472-A | MICROBIOCIDES | SCHERING AKTIENGESELLSCHAFT (DT) | 1977-10-11 | — | — | US | disclosed |