Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.53 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | CHEK2 | O96017 | 10/20 | 0.52 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.48 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.47 |
| ▸ | FHIT | P49789 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | MMP2 | P08253 | 1/20 | 0.42 |
| ▸ | MMP9 | P14780 | 1/20 | 0.42 |
| ▸ | MMP8 | P22894 | 1/20 | 0.42 |
| ▸ | MMP13 | P45452 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11727710 | 0.91 | CHEK2 (0.42) | HSP90AA1ESR2TDP1CHEK2NPBWR1 | |
| SCHEMBL11725733 | 0.85 | MMP2 (0.57) | NPBWR1MEN1KMT2ANPC1RAB9A | |
| SCHEMBL11722858 | 0.84 | NPBWR1 (0.59) | NPBWR1MEN1POLBKMT2ANPC1 | |
| SCHEMBL11719378 | 0.83 | NPBWR1 (0.53) | NPBWR1MEN1KMT2ANPC1RAB9A | |
| SCHEMBL11719699 | 0.81 | NPC1 (0.53) | NPBWR1MEN1POLBKMT2ANPC1 | |
| SCHEMBL11724421 | 0.80 | GUSB (0.46) | NPBWR1MEN1KMT2ANPC1RAB9A | |
| SCHEMBL11725236 | 0.80 | MMP2 (0.51) | NPBWR1MEN1POLBKMT2ANPC1 | |
| SCHEMBL8604250 | 0.80 | HSP90AA1 (0.59) | HSP90AA1ESR2TDP1CHEK2NPBWR1 | |
| SCHEMBL11721837 | 0.78 | NPBWR1 (0.41) | NPBWR1MEN1KMT2ANPC1RAB9A | |
| SCHEMBL11725726 | 0.78 | MMP2 (0.45) | NPBWR1MEN1KMT2ANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4053472-A | MICROBIOCIDES | SCHERING AKTIENGESELLSCHAFT (DT) | 1977-10-11 | — | — | US | disclosed |