Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 5/20 | 0.57 |
| ▸ | MMP9 | P14780 | 5/20 | 0.57 |
| ▸ | MMP8 | P22894 | 5/20 | 0.57 |
| ▸ | MMP13 | P45452 | 5/20 | 0.57 |
| ▸ | NPC1 | O15118 | 6/20 | 0.51 |
| ▸ | RAB9A | P51151 | 6/20 | 0.51 |
| ▸ | NPBWR1 | P48145 | 5/20 | 0.51 |
| ▸ | MAPT | P10636 | 4/20 | 0.51 |
| ▸ | HTT | P42858 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.51 |
| ▸ | RELA | Q04206 | 1/20 | 0.51 |
| ▸ | METAP2 | P50579 | 2/20 | 0.45 |
| ▸ | METAP1 | P53582 | 2/20 | 0.45 |
| ▸ | CBFB | Q13951 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11725726 | 0.90 | MMP2 (0.45) | MMP2MMP9MMP8MMP13NPC1 | |
| SCHEMBL11722858 | 0.89 | NPBWR1 (0.59) | MMP2MMP9MMP8MMP13NPC1 | |
| SCHEMBL11719378 | 0.88 | NPBWR1 (0.53) | MMP2MMP9MMP8MMP13NPC1 | |
| SCHEMBL11719699 | 0.86 | NPC1 (0.53) | MMP2MMP9MMP8MMP13NPC1 | |
| SCHEMBL11727716 | 0.85 | HSP90AA1 (0.53) | MMP2MMP9MMP8MMP13NPC1 | |
| SCHEMBL11724421 | 0.85 | GUSB (0.46) | MMP2MMP9MMP8MMP13NPC1 | |
| SCHEMBL11725236 | 0.85 | MMP2 (0.51) | MMP2MMP9MMP8MMP13NPC1 | |
| SCHEMBL11721837 | 0.83 | NPBWR1 (0.41) | MMP2MMP9MMP8MMP13NPC1 | |
| SCHEMBL11722849 | 0.82 | ALDH1A1 (0.49) | MMP2MMP9MMP8MMP13NPC1 | |
| SCHEMBL11719369 | 0.81 | NPBWR1 (0.45) | MMP2MMP9MMP8MMP13NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4053472-A | MICROBIOCIDES | SCHERING AKTIENGESELLSCHAFT (DT) | 1977-10-11 | — | — | US | disclosed |