Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | CDK2 | P24941 | 1/20 | 0.34 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17008861 | 0.78 | MAPT (0.32) | RAB9A | |
| SCHEMBL9761766 | 0.73 | RIPK1 (0.50) | HPGDMEN1KMT2ACDK2RIPK1 | |
| SCHEMBL6633135 | 0.69 | NPC1 (0.42) | HPGDRAB9ACDK2KDM4EALDH1A1 | |
| SCHEMBL6633132 | 0.69 | KDM4E (0.37) | HPGDKMT2ARAB9AKDM4EALDH1A1 | |
| SCHEMBL10061828 | 0.68 | CDC7 (0.41) | KMT2ARAB9ACDK2KDM4EALDH1A1 | |
| SCHEMBL12441774 | 0.68 | MAPT (0.35) | HPGDALDH1A1 | |
| SCHEMBL29793430 | 0.68 | ALDH1A1 (0.37) | HPGDALDH1A1NPC1 | |
| SCHEMBL19862537 | 0.67 | NPC1 (0.40) | HPGDRAB9ACDK2KDM4EALDH1A1 | |
| SCHEMBL7602015 | 0.67 | KDM4E (0.34) | HPGDRAB9ACDK2KDM4EALDH1A1 | |
| SCHEMBL11733107 | 0.67 | RAB9A (0.37) | HPGDHSP90AA1RAB9ARIPK1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4021442-A | Production of 1-alkyl-5-nitroimidazoles | BASF AKTIENGESELLSCHAFT (DT) | 1977-05-03 | — | — | US | disclosed |