Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.39 |
| ▸ | GRM5 | P41594 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.35 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | RAB9A | P51151 | 5/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11757581 | 0.76 | ALDH1A1 (0.50) | ALDH1A1MAPK1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL9472893 | 0.75 | ALDH1A1 (0.48) | ALDH1A1MAPK1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL113038 | 0.75 | ALDH1A1 (0.52) | ALDH1A1MAPK1MAOAMAOBFFAR1 | |
| SCHEMBL29901626 | 0.74 | ALDH1A1 (0.57) | ALDH1A1MAPK1MAOAMAOBFFAR1 | |
| SCHEMBL15638476 | 0.71 | ALDH1A1 (0.48) | ALDH1A1MAPK1MAOAMAOBFFAR1 | |
| SCHEMBL2420121 | 0.71 | ALDH1A1 (0.48) | ALDH1A1MAPK1MAOAMAOBFFAR1 | |
| SCHEMBL11727360 | 0.71 | CYP1A2 (0.43) | ALDH1A1CYP1A2CYP3A4CYP2D6CYP2C9 | |
| Methylphenylsulfide SCHEMBL28129657 | 0.71 | CYP1A2 (0.38) | ALDH1A1MAPK1GRM5CYP1A2CYP3A4 | |
| SCHEMBL942119 | 0.70 | ALDH1A1 (0.52) | ALDH1A1MAPK1MAOAMAOBFFAR1 | |
| SCHEMBL2420674 | 0.70 | ALDH1A1 (0.52) | ALDH1A1MAPK1MAOAMAOBFFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4048206-A | Process for the production of 1-organylsilatranes and carbofunctional derivatives thereof | VORONKOV MIKHAIL GRIGORIEVICH | 1977-09-13 | — | — | US | disclosed |