Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | MAOA | P21397 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 1/20 | 0.45 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | MGLL | Q99685 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2420121 | 0.86 | ALDH1A1 (0.48) | ALDH1A1MAPK1MAOAMAOBFFAR1 | |
| SCHEMBL29901626 | 0.79 | ALDH1A1 (0.57) | ALDH1A1MAPK1MAOAMAOBFFAR1 | |
| SCHEMBL15638476 | 0.76 | ALDH1A1 (0.48) | ALDH1A1MAPK1MAOAMAOBFFAR1 | |
| SCHEMBL8443557 | 0.76 | ESR1 (0.46) | ALDH1A1MAPK1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL19611324 | 0.76 | ALDH1A1 (0.43) | ALDH1A1MAPK1MAOAMAOBFFAR1 | |
| SCHEMBL2420674 | 0.75 | ALDH1A1 (0.52) | ALDH1A1MAPK1MAOAMAOBFFAR1 | |
| SCHEMBL1956668 | 0.75 | MAOA (0.50) | ALDH1A1MAPK1MAOAMAOBFFAR1 | |
| SCHEMBL11727752 | 0.75 | ALDH1A1 (0.46) | ALDH1A1MAPK1MAOAMAOBFFAR1 | |
| SCHEMBL6055062 | 0.74 | ALDH1A1 (0.41) | ALDH1A1MAPK1MAOAMAOBFFAR1 | |
| Hydrochloric Acid SCHEMBL6054980 | 0.73 | ALDH1A1 (0.40) | ALDH1A1MAPK1MAOAMAOBFFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 81 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018169112-A1 | ELECTROLYTE ADDITIVE FOR LITHIUM SECONDARY BATTERY AND METHOD FOR PREPARING SAME, ELECTROLYTE COMPRISING ADDITIVE AND METHOD FOR PREPARING SAME, AND LITHIUM SECONDARY BATTERY COMPRISING ADDITIVE | 울산과학기술원 | 2018-09-20 | — | — | WO | claimed |
| US-9006447-B2 | Method for preparing substituted isoxazoline compounds and their precursors 4-chloro, 4-bromo- or 4-iodobenzaldehyde oximes | BASF SE (DE) | 2015-04-14 | — | — | US | claimed |
| EP-2424862-B1 | PROCESS FOR PREPARING SUBSTITUTED ISOXAZOLINE COMPOUNDS AND THEIR PRECURSORS | BASF SE (DE) | 2014-10-08 | — | — | EP | claimed |
| US-8853410-B2 | Process for preparing substituted isoxazoline compounds and their precursors | BASF SE (DE) | 2014-10-07 | — | — | US | claimed |
| EP-2635552-A2 | METHOD FOR PREPARING SUBSTITUTED ISOXAZOLINE COMPOUNDS AND THEIR PRECURSORS 4-CHLORO, 4-BROMO- OR 4-IODOBENZALDEHYDE OXIMES | BASF SE (DE) | 2013-09-11 | — | — | EP | claimed |
| US-20130225826-A1 | Method for preparing substituted isoxazoline compounds and their precursors 4-chloro, 4-bromo- or 4-iodobenzaldehyde oximes | BASF SE (DE) | 2013-08-29 | — | — | US | claimed |
| WO-2012059441-A2 | METHOD FOR PREPARING SUBSTITUTED ISOXAZOLINE COMPOUNDS AND THEIR PRECURSORS 4-CHLORO, 4-BROMO- OR 4-IODOBENZALDEHYDE OXIMES | BASF SE (DE) | 2012-05-10 | — | — | WO | claimed |
| US-20120059171-A1 | Process for Preparing Substituted Isoxazoline Compounds and Their Precursors | BASF SE (DE) | 2012-03-08 | — | — | US | claimed |
| EP-2424862-A1 | PROCESS FOR PREPARING SUBSTITUTED ISOXAZOLINE COMPOUNDS AND THEIR PRECURSORS | BASF SE (DE) | 2012-03-07 | — | — | EP | claimed |
| US-20110130482-A1 | Process for preparing armatic thiophenyl ketones | PRETOR ROGER | 2011-06-02 | — | — | US | claimed |
| WO-2010125130-A1 | PROCESS FOR PREPARING SUBSTITUTED ISOXAZOLINE COMPOUNDS AND THEIR PRECURSORS | BASF SE (DE) | 2010-11-04 | — | — | WO | claimed |
| US-7622526-B2 | Thermoset material based on antiplasticizing polythiourethane and ophthalmic lens comprising an antiplasticized thermoset material | ESSILOR INTERNATIONAL (FR) | 2009-11-24 | — | — | US | claimed |
| EP-1670852-B1 | THERMOSETTING MATERIAL BASED ON ANTIPLASTICIZED POLYTHIOURETHANE, AND OPHTHALMIC LENS COMPRISING AN ANTIPLASTICIZED THERMOSETTING MATERIAL | ESSILOR INT (FR) | 2008-12-10 | — | — | EP | claimed |
| EP-1799638-B1 | PROCESS FOR PREPARING AROMATIC THIOPHENYL KETONES | CIBA HOLDING INC (CH) | 2008-07-30 | — | — | EP | claimed |
| EP-1799638-A1 | PROCESS FOR PREPARING AROMATIC THIOPHENYL KETONES | CIBA SPECIALTY CHEMICALS HOLDING INC. Patent Departement (CH) | 2007-06-27 | — | — | EP | claimed |
| JP-2007507574-A | — | — | 2007-03-29 | — | — | JP | claimed |
| US-20060270771-A1 | Thermoset material based on antiplasticizing polythiourethane and ophthalmic lens comprising an antiplasticized thermoset material | ESSILOR INTERNATIONAL COMPAGNIE GENERALE D'OPTIQUE (FR) | 2006-11-30 | — | — | US | claimed |
| EP-1670852-A1 | THERMOSETTING MATERIAL BASED ON ANTIPLASTICIZED POLYTHIOURETHANE, AND OPHTHALMIC LENS COMPRISING AN ANTIPLASTICIZED THERMOSETTING MATERIAL | ESSILOR INTERNATIONAL COMPAGNIE GENERALE D'OPTIQUE (FR) | 2006-06-21 | — | — | EP | claimed |
| WO-2006034966-A1 | PROCESS FOR PREPARING AROMATIC THIOPHENYL KETONES | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2006-04-06 | — | — | WO | claimed |
| WO-2005033190-A1 | THERMOSETTING MATERIAL BASED ON ANTIPLASTICIZED POLYTHIOURETHANE, AND OPHTHALMIC LENS COMPRISING AN ANTIPLASTICIZED THERMOSETTING MATERIAL | ESSILOR INTERNATIONAL (COMPAGNIE GENERALE D'OPTIQUE) (FR) | 2005-04-14 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110130482-A1 | Process for preparing armatic thiophenyl ketones | ACOT7, AGPAT2, COASY | ALDH1A1 1816/4885MAPK1 3795/4885MAOA 1709/4885 |
| US-20130225826-A1 | Method for preparing substituted isoxazoline compounds and their precursors 4-chloro, 4-bromo- or 4-iodobenzaldehyde oximes | CYP4X1, CYP4B1, AOX1 | ALDH1A1 445/4885MAPK1 3734/4885MAOA 93/4885 |
| US-20120059171-A1 | Process for Preparing Substituted Isoxazoline Compounds and Their Precursors | CYP4X1, CYP3A7, CYP1B1 | ALDH1A1 202/4885MAPK1 1466/4885MAOA 281/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.