Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NTRK1 | P04629 | 6/20 | 0.57 |
| ▸ | NTRK2 | Q16620 | 6/20 | 0.57 |
| ▸ | IGF1R | P08069 | 5/20 | 0.57 |
| ▸ | FGFR1 | P11362 | 5/20 | 0.57 |
| ▸ | NTRK3 | Q16288 | 2/20 | 0.57 |
| ▸ | GSK3A | P49840 | 3/20 | 0.50 |
| ▸ | GSK3B | P49841 | 3/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | DAO | P14920 | 1/20 | 0.44 |
| ▸ | FEN1 | P39748 | 3/20 | 0.44 |
| ▸ | CNOT7 | Q9UIV1 | 1/20 | 0.44 |
| ▸ | ERCC1 | P07992 | 2/20 | 0.43 |
| ▸ | ERCC4 | Q92889 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5198556 | 0.86 | NTRK1 (0.72) | NTRK1NTRK2IGF1RFGFR1NTRK3 | |
| SCHEMBL8472583 | 0.77 | NTRK1 (0.57) | NTRK1NTRK2IGF1RFGFR1NTRK3 | |
| SCHEMBL29251945 | 0.74 | NTRK1 (0.50) | NTRK1NTRK2IGF1RFGFR1NTRK3 | |
| SCHEMBL14950255 | 0.73 | MAPK8 (0.56) | NTRK1NTRK2IGF1RFGFR1NTRK3 | |
| SCHEMBL11684045 | 0.73 | PGR (0.54) | NTRK1NTRK2IGF1RFGFR1NTRK3 | |
| SCHEMBL11684638 | 0.73 | NTRK1 (0.53) | NTRK1NTRK2IGF1RFGFR1NTRK3 | |
| SCHEMBL11684573 | 0.73 | NTRK1 (0.53) | NTRK1NTRK2IGF1RFGFR1NTRK3 | |
| SCHEMBL21295405 | 0.73 | NTRK1 (1.00) | NTRK1NTRK2IGF1RFGFR1NTRK3 | |
| SCHEMBL21305540 | 0.73 | NTRK1 (0.61) | NTRK1NTRK2IGF1RFGFR1NTRK3 | |
| SCHEMBL11681429 | 0.73 | NTRK1 (0.49) | NTRK1NTRK2IGF1RFGFR1NTRK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4025486-A | PENTAERYTHRITOL PHOSPHITE COMBINATIONS AS ULTRAVIOLET LIGHT STABILIZERS FOR POLYOLEFINS | THE B. F. GOODRICH COMPANY (US) | 1977-05-24 | — | — | US | claimed |