SCHEMBL14950255

SCHEMBL14950255

O=c1[nH]c(=O)n(-c2ccccc2)c(=O)n1Cc1ccccc1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPK8 P45983 2/20 0.56
MAPK9 P45984 2/20 0.56
PGR P06401 1/20 0.56
NTRK1 P04629 2/20 0.53
NTRK3 Q16288 2/20 0.53
NTRK2 Q16620 2/20 0.53
IGF1R P08069 1/20 0.53
FGFR1 P11362 1/20 0.53
KMT2A Q03164 3/20 0.52
PDE4A P27815 1/20 0.52
PDE4B Q07343 1/20 0.52
PDE4C Q08493 1/20 0.52
PDE4D Q08499 1/20 0.52
TAS2R8 Q9NYW2 1/20 0.51
HPGD P15428 3/20 0.49
ALDH1A1 P00352 2/20 0.49
KDM4E B2RXH2 1/20 0.49
SMN1; SMN2 Q16637 1/20 0.49
RGS4 P49798 1/20 0.49
RGS8 P57771 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11684045 0.83 PGR (0.54) MAPK8MAPK9PGRNTRK1NTRK3
SCHEMBL5198556 0.81 NTRK1 (0.72) NTRK1NTRK3NTRK2IGF1RFGFR1
SCHEMBL29251945 0.80 NTRK1 (0.50) MAPK8MAPK9PGRNTRK1NTRK3
SCHEMBL11632467 0.80 NTRK1 (0.50) NTRK1NTRK3NTRK2IGF1RFGFR1
SCHEMBL11633842 0.78 NTRK1 (0.48) PGRNTRK1NTRK3NTRK2IGF1R
SCHEMBL38658744 0.77 KMT2A (0.56) KMT2AHPGDALDH1A1KDM4ESMN1; SMN2
SCHEMBL5402346 0.77 HPGD (0.50) KMT2AHPGDALDH1A1KDM4ESMN1; SMN2
SCHEMBL10941919 0.76 NTRK1 (0.47) MAPK8MAPK9PGRNTRK1NTRK3
SCHEMBL24327924 0.76 PGR (0.49) MAPK8MAPK9PGRKMT2APDE4A
SCHEMBL13562510 0.76 PGR (0.53) MAPK8MAPK9PGRNTRK1NTRK3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8922889-B2 Cellulose acylate film, protective film for polarizing plate, polarizing plate, and liquid crystal display device FUJIFILM CORPORATION (JP) 2014-12-30 US disclosed
US-20130120839-A1 CELLULOSE ACYLATE FILM, PROTECTIVE FILM FOR POLARIZING PLATE, POLARIZING PLATE, AND LIQUID CRYSTAL DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2013-05-16 US disclosed